Evidence map›Paper›PMID 34663295›Full record

ArticleBMC musculoskeletal disorders2021

Role of psychosocial factors on the effect of physical activity on physical function in patients after lumbar spine surgery.

Hiral Master, Renan Castillo, Stephen T Wegener, Jacquelyn S Pennings, Rogelio A Coronado, Christine M Haug, Richard L Skolasky, Lee H Riley, Brian J Neuman, Joseph S Cheng and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Hiral MasterDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA.
Renan CastilloDepartment of Health Policy & Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Stephen T WegenerDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Medicine, Baltimore, MD, USA.
Jacquelyn S PenningsDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA.
Rogelio A CoronadoDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA.
Christine M HaugDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA.
Richard L SkolaskyDepartment of Orthopaedic Surgery, Johns Hopkins Medicine, Baltimore, MD, USA.
Lee H RileyDepartment of Orthopaedic Surgery, Johns Hopkins Medicine, Baltimore, MD, USA.
Brian J NeumanDepartment of Orthopaedic Surgery, Johns Hopkins Medicine, Baltimore, MD, USA.
Joseph S ChengDepartment of Neurological Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Oran S AaronsonHowell Allen Clinic, Saint Thomas Medical Partners, Nashville, TN, USA.
Clinton J DevinDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA.
Kristin R ArcherDepartment of Orthopaedic Surgery, Center for Musculoskeletal Research, Vanderbilt University Medical Center, 1215 21st Ave South, Nashville, TN, 37232, USA. kristin.archer@vumc.org.
Vanderbilt University Medical Center · USJohns Hopkins Medicine · USJohns Hopkins University · USUniversity of Cincinnati Medical Center · US

Funding

Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
NCATS NIH HHS KL2 TR002245
6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate the longitudinal postoperative relationship between physical activity, psychosocial factors, and physical function in patients undergoing lumbar spine surgery.

methodsWe enrolled 248 participants undergoing surgery for a degenerative lumbar spine condition. Physical activity was measured using a triaxial accelerometer (Actigraph GT3X) at 6-weeks (6wk), 6-months (6M), 12-months (12M) and 24-months (24M) following spine surgery. Physical function (computerized adaptive test domain version of Patient-Reported Outcomes Measurement Information System) and psychosocial factors (pain self-efficacy, depression and fear of movement) were assessed at preoperative visit and 6wk, 6M, 12M and 24M after surgery. Structural equation modeling (SEM) techniques were utilized to analyze data, and results are represented as standardized regression weights (SRW). Overall SRW were computed across five imputed datasets to account for missing data. The mediation effect of each psychosocial factor on the effect of physical activity on physical function were computed [(SRW for effect of activity on psychosocial factor X SRW for effect of psychosocial factor on function) ÷ SRW for effect of activity on function]. Each SEM model was tested for model fit by assessing established fit indexes.

resultsThe overall effect of steps per day on physical function (SRW ranged from 0.08 to 0.19, p<0.05) was stronger compared to the overall effect of physical function on steps per day (SRW ranged from non-existent to 0.14, p<0.01 to 0.3). The effect of steps per day on physical function and function on steps per day remained consistent after accounting for psychosocial factors in each of the mediation models. Depression and fear of movement at 6M mediated 3.4% and 5.4% of the effect of steps per day at 6wk on physical function at 12M, respectively. Pain self-efficacy was not a statistically significant mediator.

conclusionsThe findings of this study suggest that the relationship between physical activity and physical function is stronger than the relationship of function to activity. However, future research is needed to examine whether promoting physical activity during the early postoperative period may result in improvement of long-term physical function. Since depression and fear of movement had a very small mediating effect, additional work is needed to investigate other potential mediating factors such as pain catastrophizing, resilience and exercise self-efficacy.

Indexed as

CatastrophizationExerciseFearHumansNeurosurgical ProceduresPainDegenerative lumbar spine conditionsDepressionFearFunctionPatient-reported outcomesSelf-efficacySpine surgerySteps per dayWalking

Identifiers

PMID34663295
PMCPMC8522146
OpenAlexW3207126443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.