Evidence map›Paper›PMID 34663209›Full record

ArticleBMC plant biology2021

OsANN4 modulates ROS production and mediates Ca

Qian Zhang, Tao Song, Can Guan, Yingjie Gao, Jianchao Ma, Xiangyang Gu, Zhiguang Qi, Xiaoji Wang, Zhengge Zhu

Open access · goldAbstract read
In one paragraph

Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Comprehensive Analysis of Annexin Family fromPlants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. The endoplasmic reticulum-localized CaFrontiers in plant science · 2026
    Article
  8. Article
  9. Article
  10. International journal of molecular sciences · 2025
    Article
  11. Annexins: central regulators of plant growth and stress signaling.Acta biochimica et biophysica Sinica · 2025
    Review
  12. Article
  13. Article
  14. The rice annexin genePlant direct · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Structure, Function, and Applications of Soybean Calcium Transporters.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qian ZhangHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Tao SongHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Can GuanHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Yingjie GaoHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Jianchao MaHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Xiangyang GuHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Zhiguang QiHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Xiaoji WangHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China.
Zhengge ZhuHebei Key Laboratory of Molecular and Cellular Biology, Key Laboratory of Molecular and Cellular Biology of the Ministry of Education, College of Life Science, Hebei Normal University, Hebei Collaboration Innovation Center for Cell Signaling, Shijiazhuang, 050024, China. zhuzhengge@hebtu.edu.cn.
Hebei Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlant annexins are calcium- and lipid-binding proteins that have multiple functions, and a significant amount of research on plant annexins has been reported in recent years. However, the functions of annexins in diverse biological processes in rice are largely unclear.

resultsHerein, we report that OsANN4, a calcium-binding rice annexin protein, was induced by abscisic acid (ABA). Under ABA treatment, the plants in which OsANN4 was knocked down by RNA interference showed some visible phenotypic changes compared to the wild type, such as a lower rooting rate and shorter shoot and root lengths. Moreover, the superoxide dismutase (SOD) and catalase (CAT) activities of the RNAi lines were significantly lower and further resulted in higher accumulation of O

conclusionsOsANN4 plays a crucial role in the ABA response, partially by modulating ROS production, mediating Ca

Indexed as

Abscisic AcidAnnexinsCalciumCalcium-Calmodulin-Dependent Protein KinasesCatalaseHydrogen PeroxideOryzaPhenotypePlant Growth RegulatorsPlant ProteinsProtein KinasesReactive Oxygen SpeciesRNA InterferenceSeedlingsSuperoxide DismutaseAbscisic AcidAnnexinsCalciumCalcium-Calmodulin-Dependent Protein Kinasescalcium-dependent protein kinase, riceCatalaseHydrogen PeroxidePlant Growth RegulatorsPlant ProteinsProtein KinasesReactive Oxygen SpeciesSuperoxide DismutaseAbscisic acidAnnexinCa2+ influxCalcium-dependent protein kinaseROS

Identifiers

PMID34663209
PMCPMC8522085
OpenAlexW3206883054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.