Evidence map›Paper›PMID 34662744›Full record

SynthesisAgeing research reviews2021

Prevalence of unwillingness and uncertainty to vaccinate against COVID-19 in older people: A systematic review and meta-analysis.

Nicola Veronese, Carlo Saccaro, Jacopo Demurtas, Lee Smith, Ligia J Dominguez, Stefania Maggi, Mario Barbagallo

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Ageing research reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 57 citations in OpenAlex.

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  13. Journal of preventive medicine and hygiene · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Nicola VeroneseGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy; College of Science, King Saud University, Riyadh, Saudi Arabia. Electronic address: nicola.veronese@unipa.it.
Carlo SaccaroGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
Jacopo DemurtasClinical and Experimental Medicine PhD Program, Università di Modena e Reggio Emilia, Modena - Azienda USL Sud Est Toscana, Grosseto, Italy.
Lee SmithCentre for Health, Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Ligia J DominguezSchool of Medicine, "Kore" University of Enna, Enna, Italy.
Stefania MaggiAging Branch, Neuroscience Institute, National Research Council, Padua, Italy.
Mario BarbagalloGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
University of Palermo · ITAnglia Ruskin University · GBNational Research Council · ITUniversità degli Studi di Enna Kore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) has been shown to have more severe health outcomes in older people specifically in relation to mortality and disability. Vaccination seems to be efficacious and safe for preventing the negative consequences of COVID-19, but vaccine hesitancy seems to be high in older adults. We therefore aimed to investigate the prevalence of unwillingness and the uncertainty to vaccinate against COVID-19 in older people and the factors that can be associated with the unwillingness to vaccinate. For this work, we searched several databases until 18th June 2021 for studies reporting the prevalence of unwillingness and the uncertainty to vaccinate against COVID-19 in people aged >60 years. A meta-analysis of the prevalence, with the correspondent 95% confidence intervals (CIs), was proposed. Factors that can be associated with the unwillingness to vaccinate against COVID-19 were explored through multivariable analyses and reported as odds ratios (ORs). Among 662 papers initially screened, we included 15 studies for a total of 9753 older adults. The prevalence of unwillingness to vaccinate against COVID-19 in older people was 27.03% (95%CI: 15.10-38.95%), whilst the correspondent figure of uncertainty was 19.33% (95%CI: 12.28-26.39). The risk of being unvaccinated was significantly higher in Hispanics (OR=1.197; 95%CI: 1.010-1.418) and in case of low education (OR=1.678; 95%CI: 1.170-2.408) and low income (OR=1.287; 95%CI: 1.127-1.469). In conclusion, the hesitancy for COVID-19 vaccination is a relevant problem in older people, particularly in those with a low income, a low level of education, and in Hispanics living in the United States.

Indexed as

COVID-19COVID-19 VaccinesAgedCross-Sectional StudiesHumansPrevalenceSARS-CoV-2UncertaintyVaccinationCOVID-19 VaccinesCOVID-19hesitancyolder adultsvaccine

Identifiers

PMID34662744
PMCPMC8516660
OpenAlexW3207107295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.