Evidence map›Paper›PMID 34662287›Full record

ArticleJMIR research protocols2021

Research on the Epidemiology of SARS-CoV-2 in Essential Response Personnel (RECOVER): Protocol for a Multisite Longitudinal Cohort Study.

Laura J Edwards, Ashley L Fowlkes, Meredith G Wesley, Jennifer L Kuntz, Marilyn J Odean, Alberto J Caban-Martinez, Kayan Dunnigan, Andrew L Phillips, Lauren Grant, Meghan K Herring and 28 more

Open access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
  2. Article
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  5. Influenza Vaccine Effectiveness Against Illness and Asymptomatic Infection in 2022-2023: A Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
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  8. Hybrid Immunity and SARS-CoV-2 Antibodies: Results of the HEROES-RECOVER Prospective Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
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  13. Severe Acute Respiratory Syndrome Coronavirus 2 Infection History and Antibody Response to 3 Coronavirus Disease 2019 Messenger RNA Vaccine Doses.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 10 institutions in 1 country.

Laura J Edwards *Abt Associates, Inc, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-1579-2074
Ashley L FowlkesCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-0620-6451
Meredith G WesleyAbt Associates, Inc, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-3408-0523
Jennifer L KuntzKaiser Permanente Northwest Center for Health Research, Portland, OR, United States.ORCID https://orcid.org/0000-0002-0017-6853
Marilyn J OdeanWhiteside Institute for Clinical Research, Duluth, MN, United States.ORCID https://orcid.org/0000-0001-6892-9543
Alberto J Caban-MartinezUniversity of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0002-5960-1308
Kayan DunniganBaylor Scott and White Health, Temple, TX, United States.ORCID https://orcid.org/0000-0002-1953-3291
Andrew L PhillipsUniversity of Utah, Salt Lake City, UT, United States.ORCID https://orcid.org/0000-0003-2320-3567
Lauren GrantCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-8656-3538
Meghan K HerringAbt Associates, Inc, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-4267-4033
Holly C GroomKaiser Permanente Northwest Center for Health Research, Portland, OR, United States.ORCID https://orcid.org/0000-0003-2866-9788
Karley RespetSt. Luke's Regional Health Care System, Duluth, MN, United States.ORCID https://orcid.org/0000-0002-2464-7277
Shawn BeitelUniversity of Arizona, Tucson, AZ, United States.ORCID https://orcid.org/0000-0003-1709-0906
Tnelda ZunieBaylor Scott and White Health, Temple, TX, United States.ORCID https://orcid.org/0000-0003-3990-7817
Kurt T HegmannUniversity of Utah, Salt Lake City, UT, United States.ORCID https://orcid.org/0000-0002-0743-1888
Archana KumarCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-7720-5448
Gregory JosephCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-0250-761X
Brandon PoeAbt Associates, Inc, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-1243-547X
Paola Louzado-FelicianoUniversity of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0002-2753-3945
Michael E SmithBaylor Scott and White Health, Temple, TX, United States.ORCID https://orcid.org/0000-0002-0897-6409
Matthew S ThieseUniversity of Utah, Salt Lake City, UT, United States.ORCID https://orcid.org/0000-0003-4505-2907
Natasha Schaefer-SolleUniversity of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0001-8166-2732
Young M YooCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-0845-2293
Carlos A SilveraUniversity of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0002-0512-8463
Julie Mayo LamberteCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0002-8134-9081
Josephine MakCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-9557-2690
L Clifford McDonaldCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-3044-5572
Matthew J StuckeyCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-4839-7265
Preeta KuttyCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-9813-8048
Melissa L ArvayCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-3502-4259
Sarang K YoonUniversity of Utah, Salt Lake City, UT, United States.ORCID https://orcid.org/0000-0002-8500-2886
Harmony L TynerSt. Luke's Regional Health Care System, Duluth, MN, United States.ORCID https://orcid.org/0000-0002-4130-0793
Jefferey L BurgessUniversity of Arizona, Tucson, AZ, United States.ORCID https://orcid.org/0000-0003-2362-9509
Danielle Rentz HuntAbt Associates, Inc, Atlanta, GA, United States.ORCID https://orcid.org/0000-0001-7363-3165
Jennifer MeeceMarshfield Clinic Research Institute, Marshfield, WI, United States.ORCID https://orcid.org/0000-0002-6486-3505
Manjusha GaglaniBaylor Scott and White Health, Temple, TX, United States.ORCID https://orcid.org/0000-0002-3952-9230
Allison L NalewayKaiser Permanente Northwest Center for Health Research, Portland, OR, United States.ORCID https://orcid.org/0000-0001-5747-4643
Mark G ThompsonCenters for Disease Control and Prevention, Atlanta, GA, United States.ORCID https://orcid.org/0000-0003-0046-3147
Centers for Disease Control and Prevention · USSchulman, Ronca & Bucuvalas · USUniversity of Miami · USUniversity of Utah · USBaylor Scott & White Health · USKaiser Permanente Center for Health Research · USSaint Luke's Health System · USUniversity of Arizona · USMarshfield Clinic · USTemple College · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

backgroundWorkers critical to emergency response and continuity of essential services during the COVID-19 pandemic are at a disproportionally high risk of SARS-CoV-2 infection. Prospective cohort studies are needed for enhancing the understanding of the incidence of symptomatic and asymptomatic SARS-CoV-2 infections, identifying risk factors, assessing clinical outcomes, and determining the effectiveness of vaccination.

objectiveThe Research on the Epidemiology of SARS-CoV-2 in Essential Response Personnel (RECOVER) prospective cohort study was designed to estimate the incidence of symptomatic and asymptomatic SARS-CoV-2 infections, examine the risk factors for infection and clinical spectrum of illness, and assess the effectiveness of vaccination among essential workers.

methodsThe RECOVER multisite network was initiated in August 2020 and aims to enroll 3000 health care personnel (HCP), first responders, and other essential and frontline workers (EFWs) at 6 US locations. Data on participant demographics, medical history, and vaccination history are collected at baseline and throughout the study. Active surveillance for the symptoms of COVID-19-like illness (CLI), access of medical care, and symptom duration is performed by text messages, emails, and direct participant or medical record reports. Participants self-collect a mid-turbinate nasal swab weekly, regardless of symptoms, and 2 additional respiratory specimens at the onset of CLI. Blood is collected upon enrollment, every 3 months, approximately 28 days after a reverse transcription polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 infection, and 14 to 28 days after a dose of any COVID-19 vaccine. From February 2021, household members of RT-PCR-confirmed participants are self-collecting mid-turbinate nasal swabs daily for 10 days.

resultsThe study observation period began in August 2020 and is expected to continue through spring 2022. There are 2623 actively enrolled RECOVER participants, including 280 participants who have been found to be positive for SARS-CoV-2 by RT-PCR. Enrollment is ongoing at 3 of the 6 study sites.

conclusionsData collected through the cohort are expected to provide important public health information for essential workers at high risk for occupational exposure to SARS-CoV-2 and allow early evaluation of COVID-19 vaccine effectiveness. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/31574.

Indexed as

cohort studyCOVID-19essential and frontline workersfirst responderhealth care personnelincidenceSARS-CoV-2vaccine effectiveness

Identifiers

PMID34662287
PMCPMC8647972
OpenAlexW3207147417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.