Evidence map›Paper›PMID 34662240›Full record

ArticleJournal of bacteriology2021

Identification of novel translated small ORFs in

Anne Stringer, Carol Smith, Kyle Mangano, Joseph T Wade

Abstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
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  6. Imported, not invented, genes prevail amongProceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne StringerWadsworth Center, New York State Department of Health, Albany, New York, USA.
Carol SmithWadsworth Center, New York State Department of Health, Albany, New York, USA.
Kyle ManganoCenter for Biomolecular Sciences, University of Illinois, Chicago, USA.
Joseph T WadeWadsworth Center, New York State Department of Health, Albany, New York, USA.ORCID 0000-0002-9779-3160

Funding

Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
Systematic Discovery and Analysis of Small Proteins and Small ORFs in MycobacteriaR01GM139277 · NIGMS · WADSWORTH CENTER · PI DERBYSHIRE, KEITH M, GRAY, TODD · 2020 to 2023
$2.2M
NCCIH NIH HHS T32 AT007533NIGMS NIH HHS R01 GM139277
6 · The paper itself

Abstract

Small proteins of <51 amino acids are abundant across all domains of life but are often overlooked because their small size makes them difficult to predict computationally, and they are refractory to standard proteomic approaches. Ribosome profiling has been used to infer the existence of small proteins by detecting the translation of the corresponding open reading frames (ORFs). Detection of translated short ORFs by ribosome profiling can be improved by treating cells with drugs that stall ribosomes at specific codons. Here, we combine the analysis of ribosome profiling data for

Indexed as

ProteomicsRibosome ProfilingAmino AcidsCodon, TerminatorEscherichia coliOpen Reading FramesProtein BiosynthesisAmino AcidsCodon, Terminator

Identifiers

PMID34662240
PMCPMC8765432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.