Evidence map›Paper›PMID 34662210›Full record

ArticleInfection and immunity2022

The Glycoprotein 340's Scavenger Receptor Cysteine-Rich Domain Promotes Adhesion of Staphylococcus aureus and Pseudomonas aeruginosa to Contact Lens Polymers.

Kwaku A Osei, Joshua L Mieher, Manisha Patel, Jason J Nichols, Champion Deivanayagam

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Colonization and Infection of Indwelling Medical Devices byInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kwaku A OseiSchool of Optometry, Department of Optometry and Vision Science, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.ORCID 0000-0002-4903-2519
Joshua L MieherSchool of Medicine, Department of Biochemistry and Molecular Genetics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Manisha PatelSchool of Medicine, Department of Biochemistry and Molecular Genetics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Jason J NicholsSchool of Optometry, Department of Optometry and Vision Science, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Champion DeivanayagamSchool of Medicine, Department of Biochemistry and Molecular Genetics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
University of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham School of MedicineUniversity of Alabama at Birmingham School of Optometry
6 · The paper itself

Abstract

Contact lenses are biomaterials worn on the eye to correct refractive errors. Bacterial adhesion and colonization of these lenses results in adverse events, such as microbial keratitis. The adsorption of tear proteins to contact lens materials enhances bacterial adhesion. Glycoprotein 340 (Gp340), a tear component, is known to promote microbial colonization in the oral cavity; however, it has not been investigated in any contact lens-related adverse event. Therefore, this study examined the adsorption of Gp340 and its recombinantly expressed scavenger receptor cysteine-rich (

Indexed as

Bacterial AdhesionContact LensesPolymersProtein Interaction Domains and MotifsAdhesins, BacterialBiofilmsHost-Pathogen InteractionsHumansHydrogelsMethacrylatesMuramidaseProtein BindingPseudomonas aeruginosaReceptors, ImmunologicSiliconesStaphylococcus aureusAdhesins, Bacterialetafilconglycoprotein 340Hydrogelslotrafilcon BMethacrylatesMuramidasePolymersReceptors, ImmunologicSiliconescontact lensContact lensetafilcon Aglycoprotein 340Glycoprotein 340lotrafilcon Bmicrobial keratitisocular surfacePseudomonas aeruginosascavenger receptor cysteine-richSraPStaphylococcus aureus

Identifiers

PMID34662210
PMCPMC8788705
OpenAlexW3206988116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.