Evidence map›Paper›PMID 34662188›Full record

ArticleAntimicrobial agents and chemotherapy2022

Critically Ill Patient with Multidrug-Resistant Acinetobacter baumannii Respiratory Infection Successfully Treated with Intravenous and Nebulized Bacteriophage Therapy.

Sohail Rao, Monica Betancourt-Garcia, Yetunde O Kare-Opaneye, Brett E Swierczewski, Jason W Bennett, Bri'Anna Horne, Joseph Fackler, Lia Patricia Suazo Hernandez, Michael J Brownstein

Open access · greenAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  11. [Potential of bacteriophage therapy in Germany: evidence and clinical relevance].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Review
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  15. The intricacies ofFrontiers in microbiology · 2025
    Review
  16. Article
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  18. Article
  19. Article
  20. Phage therapy: breathing new tactics into lower respiratory tract infection treatments.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sohail RaoDHR Health Institute for Research & Development, Edinburg, Texas, USA.ORCID 0000-0001-5027-9992
Monica Betancourt-GarciaDHR Health Institute for Research & Development, Edinburg, Texas, USA.
Yetunde O Kare-OpaneyeDHR Health Institute for Research & Development, Edinburg, Texas, USA.
Brett E SwierczewskiWalter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Jason W BennettWalter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Bri'Anna HorneAdaptive Phage Therapeutics, Gaithersburg, Maryland, USA.
Joseph FacklerAdaptive Phage Therapeutics, Gaithersburg, Maryland, USA.
Lia Patricia Suazo HernandezDHR Health Institute for Research & Development, Edinburg, Texas, USA.
Michael J BrownsteinAdaptive Phage Therapeutics, Gaithersburg, Maryland, USA.
Doctors Hospital at Renaissance · USWalter Reed Army Institute of Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospitalized patients are at risk of developing serious multidrug resistant bacterial infections. This risk is heightened in patients who are on mechanical ventilation, are immunocompromised, and/or have chronic comorbidities. We report the case of a 52-year-old critically ill patient with a multidrug resistant Acinetobacter baumannii (MDR-A) respiratory infection who was successfully treated with antibiotics and intravenous and nebulized bacteriophage therapy.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsCross InfectionPhage TherapyRespiratory Tract InfectionsAnti-Bacterial AgentsCritical IllnessDrug Resistance, Multiple, BacterialHumansMiddle AgedAnti-Bacterial AgentsAcinetobacterAcinetobacter baumanniibacteriophagebacteriophage therapymechanical ventilationmultidrug resistancemultidrug-resistant bacterial infection

Identifiers

PMID34662188
PMCPMC8765271
OpenAlexW3205720272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.