ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2022
Night-to-night variability of sleep apnea detected by cyclic variation of heart rate during long-term continuous ECG monitoring.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Impact of Obstructive Sleep Apnea-Hypopnea Syndrome Severity on Heart Rate Variability and QTc Interval in Hypertensive Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Detection and Predictors of Arrhythmia in Patients with Chronic Noncardioembolic Ischemic Stroke on Wearable Electrocardiogram Device.Asian journal of neurosurgery · 2025Article
- Seven-Day Patch ECG Monitoring During National Insurance Health Checkup Efficiently Detected Silent Atrial Fibrillation in Individuals Aged 75 Years and Older.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025Article
- Detection of sleep apnea using only inertial measurement unit signals from apple watch: a pilot-study with machine learning approach.Sleep & breathing = Schlaf & Atmung · 2025Article
- Study on OSA screening and influencing factors in community-based elderly hypertensive patients based on single-lead wearable ECG devices.Sleep & breathing = Schlaf & Atmung · 2024Article
- Piezoelectric rubber sheet sensor: a promising tool for home sleep apnea testing.Sleep & breathing = Schlaf & Atmung · 2024Article
- Night-to-night variability of sleep apnea detected by cyclic variation of heart rate during long-term continuous ECG monitoring.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022Article
- Effects of Sacubitril-Valsartan on Clinical, Echocardiographic, and Polygraphic Parameters in Patients Affected by Heart Failure With Reduced Ejection Fraction and Sleep Apnea.Frontiers in cardiovascular medicine · 2022Article
- Assessment of autonomic function by long-term heart rate variability: beyond the classical framework of LF and HF measurements.Journal of physiological anthropology · 2021Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleep apnea is common in patients with cardiovascular disease and is a factor that worsens prognosis. Holter 24-h ECG screening for sleep apnea is beneficial in the care of these patients, but due to high night-to-night variability of sleep apnea, it can lead to misdiagnosis and misclassification of disease severity.
methodsTo investigate the long-term dynamic behavior of sleep apnea, seven-day ECGs recorded with a patch ECG recorder in 120 patients were analyzed for the cyclic variation of heart rate (CVHR) during sleep periods as determined by a built-in three-axis accelerometer.
resultsThe frequency of CVHR (Fcv) showed considerable night-to-night variability (coefficient of variance, 66 ± 35%), which was consistent with the night-to-night variability in apnea-hypopnea index and oxygen desaturation index reported in earlier studies. In patients with presumed moderate-to-severe sleep apnea (Fcv > 15 cph at least one night), it was missed on 62% of nights, and on at least one night in 88% of patients. The CV of Fcv was negatively correlated with the average of Fcv, suggesting that patients with mild sleep apnea show greater night-to-night variability and would benefit from long-term assessment. The average Fcv was higher in the supine position, but the night-to-night variability was not explained by the night-to-night variability of time spent in the supine position.
conclusionsCVHR analysis of long-term ambulatory ECG recordings is useful for improving the reliability of screening for sleep apnea without placing an extra burden on patients with cardiovascular disease and their care.
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