Evidence map›Paper›PMID 34661895›Full record

ArticleAdvances in experimental medicine and biology2021

Pathogenesis and Host Immune Response in Leprosy.

Hadida Yasmin, Praveen Mathews Varghese, Sanjib Bhakta, Uday Kishore

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Interplay among differential exposure toFrontiers in immunology · 2023
    Article
  7. A review of nutrition in neuropathic pain of leprosy.Therapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Hadida YasminImmunology and Cell Biology Laboratory, Department of Zoology, Cooch Behar Panchanan Barma University, Cooch Behar, West Bengal, India.
Praveen Mathews VargheseBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, UK.
Sanjib BhaktaDepartment of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck, University of London, London, UK.
Uday KishoreBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, UK.
Brunel University of London · GBCooch Behar Panchanan Barma University · INInstitute of Structural and Molecular Biology · GB

Funding

Medical Research Council G0802079
6 · The paper itself

Abstract

Leprosy is an ancient insidious disease caused by Mycobacterium leprae, where the skin and peripheral nerves undergo chronic granulomatous infections, leading to sensory and motor impairment with characteristic deformities. Susceptibility to leprosy and its disease state are determined by the manifestation of innate immune resistance mediated by cells of monocyte lineage. Due to insufficient innate resistance, granulomatous infection is established, influencing the specific cellular immunity. The clinical presentation of leprosy ranges between two stable polar forms (tuberculoid to lepromatous) and three unstable borderline forms. The tuberculoid form involves Th1 response, characterized by a well demarcated granuloma, infiltrated by CD4

Indexed as

LeprosyHumansImmunity, CellularMycobacterium lepraeSkinT-LymphocytesFoamy macrophagesGiant cellsGranulomaLepromatous leprosyMycobacterium lapraeSchwann cellsTuberculoid leprosy

Identifiers

PMID34661895
OpenAlexW3205820937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.