ArticleThe international journal of cardiovascular imaging2022
Clinical, echocardiographic and hemodynamic predictors of right heart failure after LVAD placement.
Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Haemodynamics from Induction to Cardiopulmonary Bypass Improve Prediction of Right Ventricular Failure Following Left Ventricular Assist Device.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- SIENA Score and CVP/PCWP Predict Mid-Term Prognosis After LVAD Implantation: A Single-Center Study.Journal of cardiovascular development and disease · 2026Article
- Post-LVAD diuretic trajectories and predictors of diuretic resistance.Journal of cardiothoracic surgery · 2026Observational
- Multimodality Assessment for Durable Mechanical Circulatory Support Implantation.Diagnostics (Basel, Switzerland) · 2025Review
- Echocardiographic predictors of right ventricular failure following left ventricular assist device implantation: Systematic review and meta-analysis.Global cardiology science & practice · 2025Article
- Role for inflammatory markers in predicting right ventricular failure in mechanical assist device recipients.ESC heart failure · 2025Review
- Right Atrial Pressure/Pulmonary Capillary Wedge Pressure Ratio Predicts In-Hospital Mortality in Left Ventricular Assist Device Recipients.Journal of clinical medicine · 2025Article
- Prediction of Right Heart Failure in LVAD Candidates: Current Approaches and Future Directions.Journal of cardiovascular development and disease · 2025Review
- Assessment of Right Ventricle Function in Patients with Mitral Repair: Case Series.Annals of cardiac anaesthesia · 2025Article
- Advancing LVAD Technology: Overcoming Challenges and Shaping the Future of Mechanical Circulatory Support.Journal of clinical medicine · 2024Review
- Contemporary clinical role of echocardiography in patients with advanced heart failure.Heart failure reviews · 2024Review
- Pressure-dimension index and left ventricular sphericity index following HeartMate II and HeartMate 3 implantation.ESC heart failure · 2024Article
- Right ventricular dysfunction in left ventricular assist device candidates: is it time to change our prospective?Heart failure reviews · 2024Review
- Predicting, Recognizing, and Treating Right Heart Failure in Patients Undergoing Durable LVAD Therapy.Journal of clinical medicine · 2022Review
- Donor shortage in heart transplantation: How can we overcome this challenge?Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
18 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Right ventricular failure (RVF) after left ventricular assist device (LVAD) implant is associated with increasing morbidity and mortality. The aim of this study was to identify the best predictors of RVF post LVAD-implant among biochemical, haemodynamic and echocardiographic parameters. From 2009 to 2019, 38 patients who underwent LVAD implantation at our centre were prospectively enrolled. Preoperative clinical, laboratory, echocardiographic and haemodynamic parameters were reported. Overall, eight patients (21%) developed RVF over time, which revealed to be strongly related to overall mortality. Pulmonary artery pulsatility index (PAPi) resulted to be the most significant right heart catheterization index in discriminating RVF vs no RVF patients [(1.32 ± 0.26 vs. 3.95 ± 3.39 respectively) p = 0.0036]. Regarding transthoracic echocardiography, RVF was associated with reduced free wall right ventricular longitudinal strain (fw-RVLS) (- 7.9 ± 1.29 vs. - 16.14 ± 5.83) (p < 0.009), which was superior to other echocardiographic determinants of RVF. Among laboratory values, N-terminal pro-brain natriuretic peptide (NT-proBNP) was strongly increased in RVF patients [(10,496.13 pg/ml ± 5272.96 pg/ml vs. 2865, 5 pg/ml ± 2595.61 pg/ml) p = 0.006]. PAPi, NT-proBNP and fwRVLS were the best pre-operative predictors of RVF, a post-LVAD implant complication which was confirmed to have a great impact on survival. In particular, fwRVLS has been proven to be the strongest independent predictor.
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