Evidence map›Paper›PMID 34661816›Full record

ArticleGeroScience2022

Early onset of aging phenotype in vascular repair by Mas receptor deficiency.

Goutham Vasam, Shrinidh Joshi S, Su Yamin Miyat, Hashim Adam, Yagna P Jarajapu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Goutham VasamDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, 58108, USA.
Shrinidh Joshi SDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, 58108, USA.
Su Yamin MiyatDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, 58108, USA.
Hashim AdamDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, 58108, USA.
Yagna P JarajapuDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, 58108, USA. Yagna.Jarajapu@ndsu.edu.
North Dakota State University · US

Funding

Targeting Mas Receptor for Diabetic Vascular Disease in Older AdultsR01AG056881 · NIA · NORTH DAKOTA STATE UNIVERSITY · PI Yagna Jarajapu · 2017 to 2026
$3.2M
NIA NIH HHS R01 AG056881
6 · The paper itself

Abstract

Aging is associated with impaired vascular repair following ischemic insult, largely due to reparative dysfunctions of progenitor cells. Activation of Mas receptor (MasR) was shown to reverse aging-associated vasoreparative dysfunction. This study tested the impact of MasR-deficiency on mobilization and vasoreparative functions with aging. Wild type (WT) or MasR-deficient mice (MasR

Indexed as

Hematopoietic Stem Cell MobilizationHeterocyclic CompoundsAgingAnimalsMicePhenotypeStem CellsHeterocyclic CompoundsAgingIschemiaMas receptorVasculogenic progenitor cells

Identifiers

PMID34661816
PMCPMC8810970
OpenAlexW3206351908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.