Trial reportDer Anaesthesist2021
Erector spinae plane block reduces pain after laparoscopic cholecystectomy.
Trial report in Der Anaesthesist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06663449 (Comparison of ESP Block and STAP Plane Block in Laparoscopic Cholecystectomy Surgery), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of ESP Block and STAP Plane Block in Laparoscopic Cholecystectomy Surgery
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Erector spinae plane block for laparoscopic surgeries: a systematic review and meta-analysis.BMC anesthesiology · 2024Pooled it
- Efficacy of erector spinae plane block for postoperative analgesia lumbar surgery: a systematic review and meta-analysis.BMC anesthesiology · 2023Pooled it
- Single-shot regional anesthesia for laparoscopic cholecystectomies: a systematic review and network meta-analysis.Korean journal of anesthesiology · 2023Pooled it
- Analgesic effect of erector spinae plane block in adults undergoing laparoscopic cholecystectomy: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2023Pooled it
- Comparison of Ultrasound-Guided Quadratus Lumborum Plane Block and External Oblique Intercostal Plane Block for Postoperative Analgesia After Laparoscopic Cholecystectomy: A Two-Center Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Bilateral erector spinae plane block by multiple injection for pain control in pseudomyxoma peritonei surgery: a single-blind randomized controlled trial.BMC anesthesiology · 2024Trial
- Bilateral external oblique intercostal plane block (EOIPB) in patients undergoing laparoscopic cholecystectomy: A randomized controlled trial.Saudi medical journal · 2023Trial
- Erector spinae plane block in laparoscopic cholecystectomy: cutting pain, not just gallbladder (systematic review and meta-analysis of randomized controlled trials).International journal of surgery (London, England) · 2026Article
- Comparison of the Analgesic Effect and Recovery Quality Between Erector Spinae Plane Block and Quadratus Lumborum Plane Block in Laparoscopic Cholecystectomy: A Retrospective Study.Journal of pain research · 2026Article
- Ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) for postoperative analgesia in laparoscopic cholecystectomy: a randomized controlled trial.Annals of medicine and surgery (2012) · 2025Article
- Ultrasound-guided unilateral versus bilateral erector spinae plane block for postoperative analgesia of patients undergoing laparoscopic cholecystectomy.Open medicine (Warsaw, Poland) · 2025Article
- Comparison of the efficacy of erector spinae plane block according to the difference in bupivacaine concentrations for analgesia after laparoscopic cholecystectomy: a retrospective study.Journal of Yeungnam medical science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAfter laparoscopic cholecystectomy patients have moderate pain in the early postoperative period. According to several studies an erector spinae plane (ESP) block can be a valuable part of multimodal analgesia. Our intention was to evaluate how ESP block influences postoperative pain scores and opioid consumption after laparoscopic cholecystectomy.
methodsThis single-blinded, prospective, randomized study included 60 patients undergoing laparoscopic cholecystectomy to receive either bilateral ESP block at the Th 7 level (n = 30) with 20 ml of 0.25% levobupivacaine plus dexamethasone 2 mg per side, or standard multimodal analgesia (n = 30). Patients from the standard multimodal analgesia group received tramadol 100 mg at the end of the procedure. Postoperative analgesia for both groups was acetaminophen 1 g/8 h i.v. and ketorolac 30 mg/8 h. Tramadol 1 mg/kg was a rescue treatment for pain breakthrough (numeric rating scale/NRS ≥ 6) in both groups. Pain at rest was recorded at 10 min, 30 min, 2 h, 4 h, 8 h, 12 h and 24 h after surgery using NRS (0-10).
resultsAn ESP block significantly reduced postoperative pain scores compared to standard multimodal analgesia after 10 min (p = 0.011), 30 min (p = 0.004), 2 h (p = 0.011), 4 h (p = 0.003), 8 h (p = 0.013), 12 h (p = 0.004) and 24 h (p = 0.005). Tramadol consumption was significantly lower in the ESP group 25.02 ± 56.8g than in the standard analgesia group 208.3 ± 88.1g (p < 0.001).
conclusionAn ESP block can provide superior postoperative analgesia and reduction in opioid requirement after laparoscopic cholecystectomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.