Evidence map›Paper›PMID 34661682›Full record

Trial reportDer Anaesthesist2021

Erector spinae plane block reduces pain after laparoscopic cholecystectomy.

Vladimir Vrsajkov, Nataša Ilić, Arsen Uvelin, Radomir Ilić, Mirka Lukić-Šarkanović, Aleksandra Plećaš-Đurić

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Der Anaesthesist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06663449 (Comparison of ESP Block and STAP Plane Block in Laparoscopic Cholecystectomy Surgery), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06663449 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of ESP Block and STAP Plane Block in Laparoscopic Cholecystectomy Surgery

TypeinterventionalSponsorKocaeli UniversityRan2024 to 2025Enrolled68ConditionsPostoperative PainArmssubcostal transversus abdominis plane block, erector spinae plane block
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vladimir VrsajkovClinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia. vladimir.vrsajkov@gmail.com.
Nataša IlićClinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia.
Arsen UvelinClinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia.
Radomir IlićClinic of abdominal and endocrine surgery, Novi Sad, Serbia.
Mirka Lukić-ŠarkanovićClinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia.
Aleksandra Plećaš-ĐurićClinical Centre of Vojvodina, Hajduk Veljkova 1-7, 21000, Novi Sad, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAfter laparoscopic cholecystectomy patients have moderate pain in the early postoperative period. According to several studies an erector spinae plane (ESP) block can be a valuable part of multimodal analgesia. Our intention was to evaluate how ESP block influences postoperative pain scores and opioid consumption after laparoscopic cholecystectomy.

methodsThis single-blinded, prospective, randomized study included 60 patients undergoing laparoscopic cholecystectomy to receive either bilateral ESP block at the Th 7 level (n = 30) with 20 ml of 0.25% levobupivacaine plus dexamethasone 2 mg per side, or standard multimodal analgesia (n = 30). Patients from the standard multimodal analgesia group received tramadol 100 mg at the end of the procedure. Postoperative analgesia for both groups was acetaminophen 1 g/8 h i.v. and ketorolac 30 mg/8 h. Tramadol 1 mg/kg was a rescue treatment for pain breakthrough (numeric rating scale/NRS ≥ 6) in both groups. Pain at rest was recorded at 10 min, 30 min, 2 h, 4 h, 8 h, 12 h and 24 h after surgery using NRS (0-10).

resultsAn ESP block significantly reduced postoperative pain scores compared to standard multimodal analgesia after 10 min (p = 0.011), 30 min (p = 0.004), 2 h (p = 0.011), 4 h (p = 0.003), 8 h (p = 0.013), 12 h (p = 0.004) and 24 h (p = 0.005). Tramadol consumption was significantly lower in the ESP group 25.02 ± 56.8g than in the standard analgesia group 208.3 ± 88.1g (p < 0.001).

conclusionAn ESP block can provide superior postoperative analgesia and reduction in opioid requirement after laparoscopic cholecystectomy.

Indexed as

AnalgesiaCholecystectomy, LaparoscopicNerve BlockHumansPostoperative PainProspective StudiesUltrasonography, InterventionalMultimodal analgesiaNerve blockPain managementPostoperativeUltrasound

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.