Evidence map›Paper›PMID 34661666›Full record

ArticleJAMA network open2021

Estimated Cost-effectiveness of Genetic Testing in Siblings of Newborns With Cancer Susceptibility Gene Variants.

Grace O'Brien, Kurt D Christensen, Haley K Sullivan, Natasha K Stout, Lisa Diller, Jennifer M Yeh, Ann Chen Wu

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Benefits, harms, and costs of newborn genetic screening for hypertrophic cardiomyopathy: Estimates from the PreEMPT model.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Grace O'BrienBoston Children's Hospital, Boston, Massachusetts.
Kurt D ChristensenHarvard Pilgrim Health Care Institute, Boston, Massachusetts.
Haley K SullivanHarvard Pilgrim Health Care Institute, Boston, Massachusetts.
Natasha K StoutHarvard Pilgrim Health Care Institute, Boston, Massachusetts.
Lisa DillerHarvard Medical School, Boston, Massachusetts.
Jennifer M YehBoston Children's Hospital, Boston, Massachusetts.
Ann Chen WuBoston Children's Hospital, Boston, Massachusetts.
Harvard University · USBoston Children's Hospital · USBoston Children's Museum · USHarvard Pilgrim Health Care · US

Funding

Precision Medicine Policy and Treatment (PreEMPT) Model IIR01HD090019 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Kurt Derek Christensen · 2017 to 2026
$5.7M
Cost-effectiveness of Whole Genome Sequencing of Healthy AdultsK01HG009173 · NHGRI · HARVARD PILGRIM HEALTH CARE, INC. · PI CHRISTENSEN, KURT DEREK · 2016 to 2020
$626k
NHGRI NIH HHS K01 HG009173NICHD NIH HHS R01 HD090019
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cost-Benefit AnalysisFemaleGenetic Predisposition to DiseaseGenetic TestingHumansInfant, NewbornMaleMutationNeoplasms

Identifiers

PMID34661666
PMCPMC8524309
OpenAlexW3206681793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.