ArticleEuropean heart journal open2021
Pericoronary and periaortic adipose tissue density are associated with inflammatory disease activity in Takayasu arteritis and atherosclerosis.
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Article in European heart journal open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24citing papers in PubMed
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24 citing papers in PubMed, 34 citations in OpenAlex.
- Exploration of the Effects of SGLT-2 Inhibitors and GLP-1 Receptor Agonists on Coronary Inflammation in Type 2 Diabetes Patients Based on the Peri-Coronary Fat Attenuation Index.Reviews in cardiovascular medicine · 2026Article
- Coronary Plaque Vulnerability and Pericoronary Adipose Tissue Inflammation: Emerging Insights from Advanced CT Imaging.Medicina (Kaunas, Lithuania) · 2026Review
- Article
- A new predictor of disease activity in Takayasu's arteritis patients: pericarotid fat density.BMC medical imaging · 2025Article
- Serial assessment of coronary artery inflammation using cardiac CT in anthracycline chemotherapy for breast cancer.European radiology · 2025Article
- Computed tomography-based assessment of pericoronary adipose tissue in cardiovascular diseases: Diagnostic and prognostic implications.World journal of radiology · 2025Review
- Phenotyping atherosclerotic plaque and perivascular adipose tissue: signalling pathways and clinical biomarkers in atherosclerosis.Nature reviews. Cardiology · 2025Review
- Epicardial Adipose Tissue: A Multimodal Imaging Diagnostic Perspective.Medicina (Kaunas, Lithuania) · 2025Review
- Exploring the effect of dapagliflozin on coronary inflammation in type 2 diabetes patients based on the coronary artery perivascular fat attenuation index.Cardiovascular diabetology · 2025Article
- Assessment of Attenuation in Pericarotid Fat among Patients with Carotid Plaque and Spontaneous Carotid Dissection.AJNR. American journal of neuroradiology · 2025Article
- Quantifying the link: coronary artery inflammation via CCTA-derived fat attenuation index and its association with diabetes duration.Frontiers in endocrinology · 2025Article
- Pericoronary Fat Attenuation: Diagnosis and Clinical Implications.Current atherosclerosis reports · 2024Review
- Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024Review
- Multimodality imaging to assess diagnosis and evaluate complications of large vesselarteritis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2024Review
- Computed tomography pericoronary adipose tissue density predicts coronary allograft vasculopathy and adverse clinical outcomes after cardiac transplantation.European heart journal. Cardiovascular Imaging · 2024Article
- Chinese guideline for the diagnosis and treatment of Takayasu's arteritis (2023).Rheumatology and immunology research · 2024Review
- Pericoronary adipose tissue attenuation in patients with acute aortic dissection based on coronary computed tomography angiography.Quantitative imaging in medicine and surgery · 2024Article
- Novel Imaging Approaches to Cardiac Manifestations of Systemic Inflammatory Diseases: JACC Scientific Statement.Journal of the American College of Cardiology · 2023Review
- Epicardial and Pericoronary Adipose Tissue, Coronary Inflammation, and Acute Coronary Syndromes.Journal of clinical medicine · 2023Review
- Analysis of coronary computed tomography angiography-derived pericoronary fat attenuation index characteristics in the diagnostic assessment of patients with Takayasu arteritis.Quantitative imaging in medicine and surgery · 2023Article
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Authors and funding
27 authors at 10 institutions in 3 countries.
Christopher WallDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Yuan HuangEPSRC Centre for Mathematical Imaging in Healthcare, University of Cambridge, Cambridge, UK.
Elizabeth P V LeDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Andrej ĆorovićDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Christopher P UyVascular Sciences, National Heart & Lung Institute, Faculty of Medicine, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK.
Deepa GopalanDepartment of Radiology, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge, CB2 2QQ, UK.ORCID https://orcid.org/0000-0001-8079-205X
Chuoxin MaMRC Biostatistics Unit, University of Cambridge, Cambridge, UK.
Roido ManavakiDepartment of Radiology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Tim D FryerDepartment of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Luigi AlojDepartment of Radiology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Martin J GravesDepartment of Radiology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Enrico TombettiDepartment of biomedical Sciences L. Sacco, Università degli Studi di Milano, Milan, Italy.
Ben AriffDepartment of Radiology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, W12 0HS, UK.
Paul BambroughDepartment of Cardiology, Royal Papworth Hospital, Cambridge, UK CB2 0AY, UK.
Stephen P HooleDepartment of Cardiology, Royal Papworth Hospital, Cambridge, UK CB2 0AY, UK.ORCID https://orcid.org/0000-0002-3530-3808
Rosemary A RuskDepartment of Cardiology, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge, CB2 2QQ, UK.
David R JayneDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Marc R DweckCentre for Cardiovascular Science, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
David NewbyCentre for Cardiovascular Science, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.
Zahi A FayadBioMedical Engineering & Imaging Institute, Icahn School of Medicine at Mt Sinai, Gustave L. Levy Place, New York, NY 10029-5674, USA.
Martin R BennettDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
James E PetersCentre for Inflammatory Diseases, Imperial College London, London, UK.
Piotr SlomkaDepartment of Medicine, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA.ORCID https://orcid.org/0000-0002-6110-938X
Damini DeyBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, 116 N Robertson Blvd, Los Angeles, CA, 90048, USA.ORCID https://orcid.org/0000-0003-2236-6970
Justin C MasonVascular Sciences, National Heart & Lung Institute, Faculty of Medicine, Imperial College London, Hammersmith Campus, DuCane Road, London, W12 0HS, UK.ORCID https://orcid.org/0000-0001-7783-1660
James H F RuddDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.
Jason M TarkinDivision of Cardiovascular Medicine, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2QQ, UK.ORCID https://orcid.org/0000-0002-9132-120X
University of Cambridge · GBImperial College London · GBCedars-Sinai Medical Center · USImperial College Healthcare NHS Trust · GBPapworth Hospital · GBUniversity of Edinburgh · GBCambridge University Hospitals NHS Foundation Trust · GBEngineering and Physical Sciences Research Council · GBIcahn School of Medicine at Mount Sinai · USUniversity of Milan · IT
Funding
Integrated prediction of cardiovascular events by automated coronary plaque and pericoronary adipose tissue quantification from CT AngiographyR01HL148787 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI DEY, DAMINI · 2020 to 2023
$3.0MIntegrated analysis of coronary anatomy and biology with 18F-fluoride PET and CT angiographyR01HL135557 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2017 to 2020
$3.0MGa68-DOTATATE PET imaging of plaque inflammationR01HL135878 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2017 to 2020
$2.9MBritish Heart Foundation CH/2000003/12800British Heart Foundation FS/13/77/30488British Heart Foundation FS/14/78/31020British Heart Foundation FS/CRTF/20/24035Medical Research Council MR/N011775/1Medical Research Council MR/S004068/2NHLBI NIH HHS R01 HL135557NHLBI NIH HHS R01 HL135878NHLBI NIH HHS R01 HL148787Wellcome Trust 211100/Z/18/Z
Abstract
aimsTo examine pericoronary adipose tissue (PCAT) and periaortic adipose tissue (PAAT) density on coronary computed tomography angiography for assessing arterial inflammation in Takayasu arteritis (TAK) and atherosclerosis. METHODS AND
resultsPCAT and PAAT density was measured in coronary (
conclusionsPCAT and PAAT density are higher in TAK than atherosclerotic CAD or controls and are associated with clinical, biochemical, and PET markers of inflammation. Owing to excellent diagnostic accuracy, PCAT density could be useful as a clinical adjunct for assessing disease activity in TAK.
Indexed as
Coronary artery diseasePericoronary adipose tissue densityTakayasu arteritis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.