Evidence map›Paper›PMID 34660917›Full record

ArticlePhysics and imaging in radiation oncology2021

Intrafractional motion models based on principal components in Magnetic Resonance guided prostate radiotherapy.

Samuel Fransson, David Tilly, Anders Ahnesjö, Tufve Nyholm, Robin Strand

Open access · goldAbstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
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  4. Gaussian primitives for deformable image registration.Physics and imaging in radiation oncology · 2025
    Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Samuel FranssonDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
David TillyDepartment of Medical Physics, Akademiska Hospital, Uppsala, Sweden.
Anders AhnesjöDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Tufve NyholmDepartment of Radiation Sciences, Umeå University, Umeå, Sweden.
Robin StrandDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Uppsala University · SEUmeå University · SEUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDevices that combine an MR-scanner with a Linac for radiotherapy, referred to as MR-Linac systems, introduce the possibility to acquire high resolution images prior and during treatment. Hence, there is a possibility to acquire individualised learning sets for motion models for each fraction and the construction of intrafractional motion models. We investigated the feasibility for a principal component analysis (PCA) based, intrafractional motion model of the male pelvic region. MATERIALS AND

methods4D-scans of nine healthy male volunteers were utilized, FOV covering the entire pelvic region including prostate, bladder and rectum with manual segmentation of each organ at each time frame. Deformable image registration with an optical flow algorithm was performed for each subject with the first time frame as reference. PCA was performed on a subset of the resulting displacement vector fields to construct individualised motion models evaluated on the remaining fields.

resultsThe registration algorithm produced accurate registration result, in general DICE overlap

conclusionsAn individualised intrafractional male pelvic motion model is feasible. Geometric accuracy was about 1 mm based on 1-2 principal components.

Indexed as

Intrafractional motionPrincipal component analysisProstate cancer

Identifiers

PMID34660917
PMCPMC8502906
OpenAlexW3204045798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.