ArticleInternational journal of cardiology. Heart & vasculature2021
Electrocardiographic QRS duration is influenced by body mass index and sex.
Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Native QRS duration and outcomes in heart failure with mildly reduced ejection fraction: results from a large-scaled registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Sex-Based Differences in Left Bundle Branch Capture During Left Bundle Branch Area Pacing.Pacing and clinical electrophysiology : PACE · 2026Article
- Body surface potential driven personalisation of electrophysiological digital twins in hypertrophic cardiomyopathy.PLoS computational biology · 2026Article
- Deriving novel atrial fibrillation phenotypes using a tree-based artificial intelligence-enhanced electrocardiography approach.NPJ digital medicine · 2025Article
- Developing cardiac digital twin populations powered by machine learning provides electrophysiological insights in conduction and repolarization.Nature cardiovascular research · 2025Article
- The Effect of Obesity on Repolarization and Other ECG Parameters.Journal of clinical medicine · 2024Article
- Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.PLoS genetics · 2024Article
- Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.bioRxiv : the preprint server for biology · 2023Article
- Multiple anthropometric measures and proarrhythmic 12-lead ECG indices: A mendelian randomization study.PLoS medicine · 2023Article
- Abnormal blood lipid and electrocardiogram characteristics in common mental disorders.BMC psychiatry · 2023Article
- Effects of Sex on the Susceptibility for Atrial Fibrillation in Pigs with Ischemic Heart Failure.Cells · 2023Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElectrocardiogram (ECG) measured QRS duration has been shown to influence cardiovascular outcomes. However, there is paucity of data on whether ECG QRS duration is influenced by obesity and sex in large populations.
methodsAll ECGs performed by a pathology provider over a 2-year period were included. ECGs with confounding factors and those not in sinus rhythm were excluded from the primary analysis.
resultsOf the 76,220 who met the inclusion criteria, 41,685 (55%) were females. The median age of the study cohort was 61 years (interquartile [IQR] range 48-71 years). The median QRS duration was 86 ms (IQR 80-94 ms). The median BMI was 27.6 kg/m
conclusionsIn this large cohort there was a positive association between increasing BMI and QRS duration. Females had narrower QRS duration than males at similar age and similar BMI.
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Registered trials
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