Evidence map›Paper›PMID 34660799›Full record

ArticleBioMed research international2021

Coexpression Network Analysis of lncRNA Associated with Overexpression of DNMT1 in Esophageal Epithelial Cells.

Yi Lei, Yi Xu, Xu-Feng Li, Yan Chen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yi LeiThe Medical School of Jiaxing University, Jiaxing, China.ORCID https://orcid.org/0000-0001-6927-5166
Yi XuDepartment of Health Toxicology, College of Public Health, Xinjiang Medical University, Urumqi, China.
Xu-Feng LiDepartment of Health Toxicology, College of Public Health, Xinjiang Medical University, Urumqi, China.
Yan ChenThe Medical School of Jiaxing University, Jiaxing, China.ORCID https://orcid.org/0000-0002-5729-2839
Xinjiang Medical University · CNJiaxing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening and preliminary identification of high DNMT1 expression-related lncRNA, which is involved in various interrelated signaling pathways, has led to the development of a theoretical basis for various types of disease mechanisms. Differential expression profiles of lncRNA and mRNA were identified in a microarray. Ten lncRNAs with high levels of variation were identified by qRT-PCR. KEGG and GO analyses were used to identify differentially expressed mRNAs. Six signaling pathways were selected based on the KEGG results of the lncRNA-mRNA expression network analysis. From the microarrays in the experimental and control groups, we found a total of 6987 differentially expressed lncRNAs, and 7421 differentially expressed mRNAs were obtained (

Indexed as

Gene Regulatory NetworksDNA (Cytosine-5-)-Methyltransferase 1Epithelial CellsErbB ReceptorsEsophagusGene Expression ProfilingHumansRNA, Long NoncodingRNA, MessengerTumor Suppressor Protein p53DNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanEGFR protein, humanErbB ReceptorsRNA, Long NoncodingRNA, MessengerTP53 protein, humanTumor Suppressor Protein p53

Identifiers

PMID34660799
PMCPMC8519683
OpenAlexW3203549747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.