ReviewFrontiers in surgery2021
The Use of Botulinum Toxin in Complex Hernia Surgery: Achieving a Sense of Closure.
Review in Frontiers in surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06485440 (The Effects of Preoperative Botulinum Toxin A Injection Prior to Abdominal Wall Reconstruction Procedures on Respiratory System Function), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Preoperative Botulinum Toxin A Injection Prior to Abdominal Wall Reconstruction Procedures on Respiratory System Function
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preoperative botulinum toxin for complex abdominal wall reconstruction: a meta-analysis of propensity-score matched studies with trial sequential analysis.Hernia : the journal of hernias and abdominal wall surgery · 2025Pooled it
- Preoperative botulinum toxin a enables fascial closure and reduces morbidity in complex incisional hernias: results from the BRIDGE-HERNIA study.Hernia : the journal of hernias and abdominal wall surgery · 2026Observational
- Article
- Management of multi-recurrent giant incisional hernia with loss of domain: a multimodal approach using BTA, PPP, and TAR with peritoneal bridging.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Long-Term Outcomes of Preoperative Botulinum Toxin Use in Abdominal Wall Reconstruction: A Propensity-Matched Analysis of More Than 5000 Patients Over 5 Years.Aesthetic surgery journal. Open forum · 2026Article
- Intraoperative Fascial Traction - From Concept to Comprehensive Application.Journal of abdominal wall surgery : JAWS · 2026Review
- Patient Experience and Surgical Outcomes of Botulinum Toxin A Treatment in Complex Abdominal Wall Hernias: A Retrospective Analysis.Journal of abdominal wall surgery : JAWS · 2026Article
- Multimodal Prehabilitation for Hernia Repair: Linking Metabolic Modulation and Mechanical Methods.Biomedicines · 2025Review
- Follow-up of complex hernia repair with intraoperative fascial traction.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Preoperative Image-guided Botulinum Toxin A Injection in Complex Abdominal Wall Hernia Repair.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025Article
- Article
- Hybrid laparoscopic repair of complex abdominal wall hernias with transabdominal partially extraperitoneal mesh fixation: preliminary results.Frontiers in surgery · 2025Article
- A Preoperative Algorithm for Loss of Domain Hernia Repair: Stratified Management Using the Tanaka Index in 50 Cases.Journal of abdominal wall surgery : JAWS · 2025Article
- Establishing a Chemical Component Relaxation Service Using Botulinum Toxin For Abdominal Wall Reconstruction: Single-Centre Experience From a UK Tertiary Hernia Referral Unit.Journal of abdominal wall surgery : JAWS · 2025Article
- Patient-Reported Outcomes After Preoperative Botulinum Toxin A Injection Prior to Abdominal Wall Hernia Surgery: An International Survey.Journal of abdominal wall surgery : JAWS · 2025Article
- Preoperative botolinum toxin A (BTA) and intraoperative fascial traction (IFT) in the management of complex abdominal wall hernias.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Exploring New and Potential Indications for Botulinum Toxin Treatment: An Updated Literature Review.Cureus · 2024Review
- Giant Inguino-Scrotal Hernia With Loss of Domain: Surgical Report and Literature Review.Cureus · 2024Article
- [The use of botulinum toxin in hernia surgery: results of a survey in certified hernia centers].Chirurgie (Heidelberg, Germany) · 2024Article
- Image guided preoperative abdominal wall botox injection for large ventral hernia repair: A case series.Radiology case reports · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal wall surgeons have developed a host of tools to help facilitate fascial closure. Botulinum toxin A is one of the most recently identified treatments and has grown in popularity over recent years; showing great promise in a number of case series and cohort studies. The toxin paralyses lateral abdominal wall muscles in order to increase laxity of the tissues-facilitating medialisation of the rectus muscles. Several research groups around the world are developing expertise with its use-uncovering its potential. We present a review of the relevant literature over the last two decades, summarising the key evidence behind its indications, dosing and effects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.