Evidence map›Paper›PMID 34660626›Full record

SynthesisFrontiers in medicine2021

Comparison of the Efficacy of Melasma Treatments: A Network Meta-Analysis of Randomized Controlled Trials.

Yi Liu, Shanshan Wu, Haixuan Wu, Xuelei Liang, Dechao Guo, Fenglin Zhuo

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Potential Cutaneous Applications ofInternational journal of molecular sciences · 2025
    Article
  10. Review
  11. Efficacy and Safety of Low-Fluence 730-nm Picosecond Laser in the Treatment of Melasma in Chinese Patients.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025
    Article
  12. Article
  13. Clinical Applications ofLife (Basel, Switzerland) · 2023
    Review
  14. Skin of colour: essentials for the non-dermatologist.Clinical medicine (London, England) · 2023
    Review
  15. Article
  16. Melasma: The need for tailored photoprotection to improve clinical outcomes.Photodermatology, photoimmunology & photomedicine · 2022
    Review
  17. Update on Melasma-Part II: Treatment.Dermatology and therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yi LiuDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Shanshan WuNational Clinical Research Center of Digestive Diseases, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Haixuan WuDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xuelei LiangDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Dechao GuoDepartment of General Surgery, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Fenglin ZhuoDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Friendship Hospital · CNThe Third Affiliated Hospital of Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

comparisonefficacymelasmanetwork meta-analysistreatment

Identifiers

PMID34660626
PMCPMC8511390
OpenAlexW3202985800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.