Evidence map›Paper›PMID 34660182›Full record

ArticleAnalytical cellular pathology (Amsterdam)2021

circ-SIRT1 Promotes Colorectal Cancer Proliferation and EMT by Recruiting and Binding to eIF4A3.

Xiangjie Wang, Shuang Liu, Bin Xu, Yabin Liu, Peng Kong, Changlin Li, Binghui Li

Open access · goldAbstract read
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. The role of SIRT1 in the development of gastrointestinal tumors.Frontiers in cell and developmental biology · 2025
    Review
  6. Article
  7. Article
  8. Emerging Role of Circular RNAs in Hepatocellular Carcinoma Immunotherapy.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiangjie WangDepartment of General Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.ORCID https://orcid.org/0000-0001-8869-5596
Shuang LiuDepartment of General Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Bin XuDepartment of General Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yabin LiuDepartment of General Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Peng KongDepartment of Biochemistry and Molecular Biology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei, China.
Changlin LiDepartment of Biochemistry and Molecular Biology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei, China.
Binghui LiDepartment of General Surgery, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.ORCID https://orcid.org/0000-0002-4070-397X
Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNA (circRNA), a recently identified type of endogenous noncoding RNA, has been implicated in the occurrence and development of a variety of tumors; however, whether circ-SIRT1, derived from pre-mRNA of the parental

Indexed as

Cell ProliferationEpithelial-Mesenchymal TransitionAdultAgedAged, 80 and overAntigens, CDCadherinsColorectal NeoplasmsDEAD-box RNA HelicasesEukaryotic Initiation Factor-4AFemaleGene Expression Regulation, NeoplasticHCT116 CellsHT29 CellsHumansMaleAntigens, CDCadherinsCDH2 protein, humanDEAD-box RNA HelicasesEIF4A3 protein, humanEukaryotic Initiation Factor-4ARNA, CircularVimentinVIM protein, human

Identifiers

PMID34660182
PMCPMC8519704
OpenAlexW3207331941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.