Evidence map›Paper›PMID 34660142›Full record

ArticleCureus2021

Utilization Trends and Predictors of Non-invasive and Invasive Ventilation During Hospitalization Due to Community-Acquired Pneumonia.

Harshil Shah, Jude ElSaygh, Abdur Raheem, Mohammed A Yousuf, Lac Han Nguyen, Pratiksha S Nathani, Venus Sharma, Abhinay Theli, Maheshkumar K Desai, Dharmeshkumar V Moradiya and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Harshil ShahInternal Medicine, Guthrie Robert Packer Hospital, Sayre, USA.
Jude ElSayghInternal Medicine, University of Debrecen, Debrecen, HUN.
Abdur RaheemInternal Medicine, Texas Tech University Health Sciences Center at Permian Basin, Odessa, USA.
Mohammed A YousufGeneral Medicine, Gleneagles Global Hospitals, Hyderabad, IND.
Lac Han NguyenInternal Medicine, University of Medicine and Pharmacy of Ho Chi Minh City, Ho Chi Minh City, VNM.
Pratiksha S NathaniInternal Medicine, Maharashtra University of Health Sciences, Nashik, IND.
Venus SharmaInternal Medicine, Punjab Institute of Medical Sciences, Jalandhar, IND.
Abhinay TheliInternal Medicine, Guthrie Cortland Medical Center, Cortland, USA.
Maheshkumar K DesaiInternal Medicine, Hamilton Medical Center, Medical College of Georgia/Augusta University, Augusta, USA.
Dharmeshkumar V MoradiyaInternal Medicine, St John of God Murdoch Hospital, Murdoch, AUS.
Hiteshkumar DevaniDental Medicine, University of Pittsburgh School of Dental Medicine, Pittsburgh, USA.
Apurwa KarkiCritical Care, Guthrie Cortland Medical Center, Cortland, USA.
Punjab Institute of Medical Sciences · INSUNY Upstate Medical University · USTexas Tech University · USUniversity of Debrecen · HUUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCommunity-acquired pneumonia (CAP) is associated with significant morbidity and mortality. Non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV) are most important interventions for patients with severe CAP associated with respiratory failure. We analysed utilization trends and predictors of non-invasive and invasive ventilation in patients hospitalized with CAP.

methodsNationwide Inpatient Sample and Healthcare Cost and Utilization Project data for years 2008-2017 were analysed. Adult hospitalizations due to CAP were identified by previously validated International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) and International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes. We then utilized the Cochran-Armitage trend test and multivariate survey logistic regression models to analyse temporal incidence trends, predictors, and outcomes. We used SAS 9.4 software (SAS Institute Inc., Cary, NC, USA) for analysing data.

resultsOut of a total of 8,385,861 hospitalizations due to CAP, ventilation assistance was required in 552,395 (6.6%). The overall ventilation use increased slightly; however, IMV utilization decreased, while NIV utilization increased. In multivariable regression analysis, males, Asian/others and weekend admissions were associated with higher odds of any ventilation utilization. Concurrent diagnoses of septicemia, congestive heart failure, alcoholism, chronic lung diseases, pulmonary circulatory diseases, diabetes mellitus, obesity and cancer were associated with increased odds of requiring ventilation assistance. Ventilation requirement was associated with high odds of in-hospital mortality and discharge to facility.

conclusionThe use of NIV among CAP patients has increased while IMV use has decreased over the years. We observed numerous factors linked with a higher use of ventilation support. The requirement of ventilation support is also associated with very high chances of mortality and morbidity.

Indexed as

community acquired pneumoniainvasive mechanical ventilationnon-invasive ventilationoutcomestrends

Identifiers

PMID34660142
PMCPMC8515501
OpenAlexW3201116814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.