Evidence map›Paper›PMID 34660044›Full record

ArticleCureus2021

SARS-COV-2 Infection in Children and Red Blood Cell Distribution Width.

Hyppolite Tchidjou Kuekou, Lucia Palandri, Suzanne Pouplin, Valerie LiThiao Te, Elena Righi, Sandrine Castelain, Jannick Ricard

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Dynamic characteristics of COVID-19 infection in Chinese children.American journal of translational research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hyppolite Tchidjou KuekouPediatric Emergency Services, Amiens University Hospital, Amiens, FRA.
Lucia PalandriDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, ITA.
Suzanne PouplinPediatric Emergency Services, Amiens University Hospital, Amiens, FRA.
Valerie LiThiao TeDepartment of Pediatric Hematology/Oncology, Amiens University Hospital, Amiens, FRA.
Elena RighiDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, ITA.
Sandrine CastelainDepartment of Microbiology, Amiens University Hospital, Amiens, FRA.
Jannick RicardPediatric Emergency Services, Amiens University Hospital, Amiens, FRA.
University of Modena and Reggio Emilia · ITCentre Hospitalier Universitaire Amiens-Picardie · FRUniversité de Picardie Jules Verne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-COV-2 infection due to Coronavirus is highly contagious and causes varying degrees of illness throughout the world. Recent literature has shown an association between red blood cell distribution width (RDW) and adverse outcomes among adult patients with COVID-19. Multiple hypotheses can explain the potential prognostic role of RDW in COVID-19 infection. The aim of this study is to describe RDW values in SARS-COV-2 infected children admitted to the Pediatric Emergency Department to shed light on the potential role of RDW as a prognostic factor in this specific group. Of 1086 tested children observed from March 2020 to April 2021, 36 positive SARS-COV-2 children (0-16 years) did not show clinically significant differences in RDW values according to illness categories, days of hospitalization, presence of multisystem inflammatory syndrome in children (MIS-C), or viral load (cycle threshold (CT) values). This study is the first to investigate this issue in a SARS-COV-2 infected pediatric population. Despite our negative results, given the high incidence of Delta variant in children, the low cost of the examination, its prognostic role described in adults, and its association to other pediatric illnesses, we believe that the role of RDW in SARS-COV-2 infected children should be deeper assessed and that larger collaborative studies on this issue are required.

Indexed as

clinical outcomescovid-19covid-19 outcome predictorerythrocyte indicespediatrics emergencyprognostic rolered blood cell distribution width (rdw)sars-cov-2 in childrenseverity of disease

Identifiers

PMID34660044
PMCPMC8501313
OpenAlexW3196973866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.