ArticleCase reports in ophthalmological medicine2021
Nonarteritic Anterior Ischemic Optic Neuropathy following COVID-19 Vaccination: Consequence or Coincidence.
Article in Case reports in ophthalmological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- A Systematic Review of Ocular Complications Following Different Types of Covid-19 Vaccines.Journal of immunology research · 2025Pooled it
- Cranial neuropathy following coronavirus disease 2019 vaccination in kidney transplant recipients.IJU case reports · 2024Article
- Non-arteritic Anterior Ischemic Optic Neuropathy Sequela From Potential COVID-19-Associated Coagulopathy.Cureus · 2024Article
- Long-term follow-up of a young male who developed acute macular neuroretinopathy following COVID-19 vaccination.Clinical case reports · 2023Article
- Neuro-Ophthalmic Complications of COVID-19 Infection and Vaccination.Advances in ophthalmology and optometry · 2023Review
- Three Cases of Arteritic Anterior Optic Neuropathy Several Months after COVID-19 Vaccination.Case reports in ophthalmological medicine · 2023Article
- Review
- Review
- Neuro-ophthalmic Sequelae in COVID-19 Recovered Cases.Indian journal of ophthalmology · 2022Article
- A Case of Atypical Unilateral Optic Neuritis Following BNT162b2 mRNA COVID-19 Vaccination.Vaccines · 2022Article
- Non-arteritic anterior ischemic optic neuropathy in COVID-19 infection - A case report.American journal of ophthalmology case reports · 2022Article
- Ocular adverse effects of COVID-19 vaccines: A systematic review.Journal of family medicine and primary care · 2022Review
- Article
- Non-arteritic anterior ischaemic optic neuropathy (NA-AION) and COVID-19 vaccination.BMJ case reports · 2022Article
- Ischemic Optic Neuropathy After Administration of a SARS-CoV-2 Vaccine: A Report of 2 Cases.The American journal of case reports · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To report a patient with nonarteritic anterior ischemic optic neuropathy (NA-AION) occurring soon after the COVID-19 vaccination. A 55-year-old woman presented with a 4-day history of inferior visual field disturbance in the right eye 7 days after receiving the first dose of Pfizer-BioNTech COVID-19 vaccine. Examination revealed a best-corrected visual acuity of 20/20 in both eyes. A relative afferent pupillary defect was observed in the right eye. Fundoscopy revealed diffuse optic disc swelling in the right eye, which was prominent above the optic disc. Goldmann visual field testing identified an inferior altitudinal visual field defect with I/2 isopter in the right eye. Although typical complete inferior visual field defect was not detected, a diagnosis of NA-AION was made. The patient was followed without any treatment. During the 2-month follow-up period, the optic disc swelling was gradually improved, and visual acuity was maintained 20/20; however, the optic disc looked diffusely pale in the right eye. Although it is uncertain whether the development of NA-AION after COVID-19 vaccination was consequential or coincidental, we speculate that the close temporal relationship with COVID-19 vaccination suggests the possibility of vasculopathy on the microvascular network of optic nerve head as background of inflammatory or immune-mediated element to the timing of the onset of NA-AION. The aim of this case report is to present this biological plausibility and to elucidate potential ophthalmological complications.
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Registered trials
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