Evidence map›Paper›PMID 34659845›Full record

ArticleCase reports in hepatology2021

A Devastating Case of Hepatitis C-Induced Mixed Cryoglobulinemia.

Sameeha Khalid, Dhuha Alhankawi, Kamalmeet Kaur, Ali Ali, Anna Kazaryan, Marina Roytman

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sameeha KhalidDepartment of Internal Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.ORCID https://orcid.org/0000-0001-9643-3473
Dhuha AlhankawiDepartment of Gastroenterology & Hepatology, University of California San Francisco-Fresno, Fresno, CA, USA.
Kamalmeet KaurDepartment of Internal Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Ali AliDepartment of Internal Medicine, University of California San Francisco-Fresno, Fresno, CA, USA.
Anna KazaryanDepartment of Rheumatology, University of California San Francisco-Fresno, Fresno, CA, USA.
Marina RoytmanDepartment of Gastroenterology & Hepatology, University of California San Francisco-Fresno, Fresno, CA, USA.
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C-induced mixed cryoglobulinemia leading to rapidly progressive gangrene, necessitating amputations, is a rare presentation. We describe a case of a 55-year-old man with untreated chronic hepatitis C virus (HCV) presenting with arthralgia and palpable purpura, which rapidly progressed to life-threatening gangrene of all extremities requiring amputations in the setting of mixed cryoglobulinemia. Treatment for HCV was initiated which led to the arrest of gangrene progression and the patient's survival. Patients with HCV-induced cryoglobulinemia should be closely monitored and started on early therapy with direct-acting antiviral therapy to prevent progression of vasculitis to gangrene. Universal screening for HCV can aid in early diagnosis and treatment to prevent devastating consequences.

Identifiers

PMID34659845
PMCPMC8519709
OpenAlexW3207834286

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.