ArticleJournal of thoracic disease2021
Development and validation of a nomogram model for early postoperative hyperlactatemia in patients undergoing cardiac surgery.
Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- The Effect of Preoperative Hydration on Cardiac Surgery-Associated Acute Kidney Injury.Brazilian journal of cardiovascular surgery · 2026Trial
- Development and Validation of an Interpretable Model for Predicting Postoperative Hyperlactatemia in Young Children Following Congenital Heart Surgery.Journal of clinical medicine · 2026Article
- Analysis of risk factors and adverse outcomes for hyperlacidemia following acute Stanford A aortic dissection.Journal of cardiothoracic surgery · 2026Article
- Postoperative lactate trajectories predict in-hospital adverse outcomes and differ by surgical approach in cardiac surgery: a propensity score-matched study.Frontiers in cardiovascular medicine · 2026Article
- Development and validation of a clinical prediction model for early ventilator weaning in post-cardiac surgery.Heliyon · 2024Article
- Nomogram and risk calculator for severe hypoxemia after heart valve surgery.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative hyperlactatemia (POHL) is common in patients undergoing cardiac surgery, associated with adverse outcomes. The aim of this study was to identify predictors for POHL after cardiac surgery and to develop and validate a predictive model.
methodsAdult patients who underwent open heart surgery at our institution between 2016 and 2019 were retrospectively included. The patients were randomly divided into training and validation groups at a 2:1 ratio. Multivariate logistic regression was performed to identify independent predictors for POHL in the training set. A nomogram was then constructed and was validated in the validation set.
resultsPOHL developed in 713 of the 5,323 patients (13.4%). The mortality rate was higher in patients with POHL compared with patients without that (9.5%
conclusionsWe identified 7 independent risk factors and derived a prediction model for POHL in patients undergoing cardiac surgery. The model may contribute significantly to early risk assessment and clinical intervention.
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