ArticleSAGE open medicine2021
Prevalence of depression and anxiety in patients with chronic obstructive pulmonary disease and their association with psychosocial outcomes: A cross-sectional study from Pakistan.
Article in SAGE open medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Global Economic and Social Burden of Chronic Obstructive Pulmonary Disease: A Systematic Review (2020-2024).International journal of chronic obstructive pulmonary disease · 2026Pooled it
- Feasibility and acceptability of the Unified Protocol for anxiety and depression in Pakistan: a pilot randomized controlled trial.BMC psychiatry · 2026Trial
- Machine learning-based cross-sectional exploration of depression-chronic pain associations in chronic respiratory disease patients.BMC geriatrics · 2026Observational
- Immune-inflammatory profiles are associated with exercise capacity and psychological status in hospitalized patients with acute exacerbation of COPD.Scientific reports · 2026Article
- Toward Holistic COPD Management: The Case for Mental Health Integration.Health science reports · 2026Article
- The interrelationship between nutritional risk, psychological factors, and quality of life in chronic obstructive pulmonary disease (COPD): a hospital-based cross-sectional study.Irish journal of medical science · 2026Article
- A Prediction Model for 9-Year Depression Risk Among Patients With COPD in China.Depression and anxiety · 2026Article
- Navigating pressure: Understanding mental health and help-seeking among female university students in Pakistan.Global mental health (Cambridge, England) · 2026Article
- Comorbid depression and autonomic dysfunction reduce lung function in patients with chronic obstructive pulmonary disease.World journal of psychiatry · 2025Article
- High Prevalence of Depression and Anxiety in Patients with Chronic Respiratory Diseases Admitted to Intensive Care in a Low-Resource Setting.Advances in respiratory medicine · 2025Article
- Determinants of generalized anxiety and construction of a predictive model in patients with chronic obstructive pulmonary disease.World journal of psychiatry · 2025Article
- Depression and anxiety disorders in chronic obstructive pulmonary disease patients: Prevalence, disease impact, treatment.World journal of psychiatry · 2024Review
- Serum levels of biomarkers that may link chronic obstructive pulmonary disease and depressive disorder.Pharmacological reports : PR · 2023Article
- Article
- Omega-3 Polyunsaturated Fatty Acids in Managing Comorbid Mood Disorders in Chronic Obstructive Pulmonary Disease (COPD): A Review.Journal of clinical medicine · 2023Review
- Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers.Archives of medical science : AMS · 2023Article
- Fatigue, Depression, and Anxiety in Patients with COPD, Asthma and Asthma-COPD Overlap.Journal of clinical medicine · 2022Article
- Flourishing despite Chronic Obstructive Pulmonary Disease (COPD): Findings from a Nationally Representative Survey of Canadians Aged 50 and Older.International journal of environmental research and public health · 2022Article
- Prevalence and Predictors of Sleep Disturbance, Anxiety and Depression among Patients with Chronic Respiratory Diseases.International journal of environmental research and public health · 2022Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesChronic obstructive pulmonary disease contributes to substantial health and economic burden worldwide. Co-morbid depression and anxiety are highly prevalent in patients with chronic obstructive pulmonary disease. Depressive symptoms in chronic obstructive pulmonary disease are associated with poorer survival, longer hospitalisation and impaired quality of life. Literature on chronic obstructive pulmonary disease is largely derived from high-income countries; yet 90% of deaths related to chronic obstructive pulmonary disease occur in low- and middle-income countries. We aimed to establish the prevalence of anxiety and depression in patients with chronic obstructive pulmonary disease, as well as the association with psychosocial outcomes.
methodsThis was a cross-sectional study of chronic obstructive pulmonary disease patients attending outpatient primary care clinics in Karachi, Pakistan. The Patient Health Questionnaire-9 was used to assess depression and the Generalised Anxiety Disorder-7 scale was used for the assessment of anxiety. Health-related quality of life was assessed with EuroQol-Five Dimensions, social support with Oslo-3 and social stress with Life Events Checklist. We recruited 293 subjects.
resultsThe prevalence of depression and anxiety in the sample was 51% (
conclusionGiven the association with reduced social support and increased perceived stress, the role of psychosocial interventions must be explored in improving outcomes of chronic obstructive pulmonary disease patients in Pakistan.
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Registered trials
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