Evidence map›Paper›PMID 34659753›Full record

ArticleClinical case reports2021

Recombinant activated factor VII in a patient with intracranial hemorrhage and severe thrombocytopenia.

Amir M Ansari, Adam Khorasanchi, Armaghan Faghihimehr, Amir Toor

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amir M AnsariDepartment of Internal Medicine Massey Cancer Center Virginia Commonwealth University Richmond Virginia US.ORCID https://orcid.org/0000-0001-5149-9786
Adam KhorasanchiDepartment of Internal Medicine Massey Cancer Center Virginia Commonwealth University Richmond Virginia US.ORCID https://orcid.org/0000-0002-4603-376X
Armaghan FaghihimehrDepartment of Radiology Virginia Commonwealth University Richmond Virginia US.
Amir ToorDepartment of Internal Medicine Massey Cancer Center Virginia Commonwealth University Richmond Virginia US.ORCID https://orcid.org/0000-0001-5317-8433
Virginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorrhage in patients with hematologic malignancies is often difficult to manage as many of these patients also have coagulopathy and thrombocytopenia of varying severity. Recombinant factor VIIa is a FDA-approved agent for management of bleeding in hemophilia patients with inhibitors. Use of recombinant FVIIa has also been used as a last resort in various clinical settings such as trauma, alveolar hemorrhage, gastrointestinal bleeding, and intracranial hemorrhage for control of bleeding with variable outcomes. This paper presents a case of recombinant FVIIa administration in a patient with multiple myeloma and profound transfusion refractory thrombocytopenia suffering from traumatic subdural hematoma.

Indexed as

intracranial hemorrhagemultiple myelomaplatelet transfusion refractorinessrecombinant activated FVIIthrombocytopenia

Identifiers

PMID34659753
PMCPMC8502438
OpenAlexW3207476941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.