Evidence map›Paper›PMID 34659735›Full record

ArticleTherapeutic advances in endocrinology and metabolism2021

Endotrophin as a novel marker in PCOS and its relation with other adipokines and metabolic parameters: a pilot study.

Gurhan Guney, Mine Islimye Taskin, Ozgur Baykan, Ertan Adali, Selin Gul Tezcan, Serkan Sarikaya, Cihan Kaya, Ezgi Tolu

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Expression of Serum Omentin, CTRP9, and Vaspin in Patients with Polycystic Ovary Syndrome.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. The estrogen receptor and metabolism.Women's health (London, England)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gurhan GuneyDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Çağıș Campus, 10145 Balıkesir, Turkey.ORCID https://orcid.org/0000-0002-0093-2743
Mine Islimye TaskinDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Ozgur BaykanDepartment of Biochemistry, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Ertan AdaliDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Selin Gul TezcanDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Serkan SarikayaDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Cihan KayaDepartment of Obstetrics and Gynaecology Acibadem Bakirkoy Hospital, Acibadem Mehmet Ali Aydinlar University, Istanbul,Turkey.
Ezgi ToluDepartment of Reproductive Endocrinology and Infertility, Medical Faculty, Balikesir University, Balıkesir, Turkey.
Balıkesir University · TRAcıbadem Adana Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome is known to be the most common hormonal disorder in women of reproductive age. Current evidence shows that regulatory proteins secreted from the adipose tissue called adipokines may have a role in polycystic ovary syndrome. We planned to investigate the role of endotrophin that has never been researched in polycystic ovary syndrome before and its correlation with other metabolic parameters and adipokines such as adiponectin and ghrelin in patients with polycystic ovary syndrome.

methodsForty-three women (

resultsTotal testosterone, homeostasis model assessment for insulin resistance, C-reactive protein, luteinizing hormone/follicle-stimulating hormone ratio, and triglyceride levels were higher in patients with polycystic ovary syndrome (

conclusionWe demonstrated that endotrophin level is higher in patients with polycystic ovary syndrome and may have predicted polycystic ovary syndrome with increased homeostasis model assessment for insulin resistance index. There was no significant difference in adiponectin and ghrelin levels in the polycystic ovary syndrome group. Endotrophin may have a role in polycystic ovary syndrome etiology rather than other adipokines.

Indexed as

adiponectinendotrophinghrelinpolycystic ovary syndrome

Identifiers

PMID34659735
PMCPMC8511906
OpenAlexW3205233001

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.