Evidence map›Paper›PMID 34659724›Full record

ArticleChemical science2021

Conversion of bile salts from inferior emulsifier to efficient smart emulsifier assisted by negatively charged nanoparticles at low concentrations.

Haojie Zhang, Miao Lv, Jianzhong Jiang, Zhenggang Cui, Wenshui Xia, Bernard P Binks

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. High-purity 1,2-dimyristoyl-Frontiers in nutrition · 2024
    Article
  5. COChemical science · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haojie ZhangThe Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University 1800 Lihu Road Wuxi Jiangsu P. R. China jzjiang@jiangnan.edu.cn.
Miao LvThe Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University 1800 Lihu Road Wuxi Jiangsu P. R. China jzjiang@jiangnan.edu.cn.
Jianzhong JiangThe Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University 1800 Lihu Road Wuxi Jiangsu P. R. China jzjiang@jiangnan.edu.cn.ORCID https://orcid.org/0000-0002-3984-6658
Zhenggang CuiThe Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University 1800 Lihu Road Wuxi Jiangsu P. R. China jzjiang@jiangnan.edu.cn.ORCID https://orcid.org/0000-0002-0006-9636
Wenshui XiaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University 1800 Lihu Road Wuxi Jiangsu P. R. China.
Bernard P BinksDepartment of Chemistry, University of Hull Hull HU6 7RX UK b.p.binks@hull.ac.uk.ORCID https://orcid.org/0000-0003-3639-8041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bile salts (BS), one of the biological amphiphiles, are usually used as solubilizing/emulsifying agents of lipids or drugs. However, BS such as sodium deoxycholate (NaDC) can't stabilize an oil-in-water (O/W) emulsion alone due to its unusual molecular structure. In this paper we report that these emulsifiers with poor emulsifying ability can be transformed to highly efficient emulsifiers by combining with negatively charged particles (silica or montmorillonite). Both together can synergistically co-stabilize oil-in-water emulsions at extremely low concentrations (minimum 0.01 mM NaDC plus 0.003 wt% particles). Moreover, the emulsions can be reversibly switched between stable and unstable triggered by CO

Identifiers

PMID34659724
PMCPMC8442726

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.