Evidence map›Paper›PMID 34659632›Full record

ArticleOxidative medicine and cellular longevity2021

Design-Based Stereology of the Lung in the Hyperoxic Preterm Rabbit Model of Bronchopulmonary Dysplasia.

Christian Mühlfeld, Henri Schulte, Johanna Christine Jansing, Costanza Casiraghi, Francesca Ricci, Chiara Catozzi, Matthias Ochs, Fabrizio Salomone, Christina Brandenberger

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  9. Article
  10. Prematurity and Hyperoxia Have Different Effects on Alveolar and Microvascular Lung Development in the Rabbit.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Christian MühlfeldInstitute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany.
Henri SchulteInstitute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany.
Johanna Christine JansingInstitute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany.
Costanza CasiraghiCorporate R&D Preclinical Department, Chiesi Farmaceutici S.p.A, Via Palermo 26/a, 43122 Parma, Italy.
Francesca RicciCorporate R&D Preclinical Department, Chiesi Farmaceutici S.p.A, Via Palermo 26/a, 43122 Parma, Italy.
Chiara CatozziCorporate R&D Preclinical Department, Chiesi Farmaceutici S.p.A, Via Palermo 26/a, 43122 Parma, Italy.
Matthias OchsInstitute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany.
Fabrizio SalomoneCorporate R&D Preclinical Department, Chiesi Farmaceutici S.p.A, Via Palermo 26/a, 43122 Parma, Italy.
Christina BrandenbergerInstitute of Functional and Applied Anatomy, Hannover Medical School, 30625 Hannover, Germany.ORCID https://orcid.org/0000-0001-9848-432X
Medizinische Hochschule Hannover · DEChiesi (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) is a complex condition frequently occurring in preterm newborns, and different animal models are currently used to mimic the pathophysiology of BPD. The comparability of animal models depends on the availability of quantitative data obtained by minimally biased methods. Therefore, the aim of this study was to provide the first design-based stereological analysis of the lungs in the hyperoxia-based model of BPD in the preterm rabbit. Rabbit pups were obtained on gestation day 28 (three days before term) by cesarean section and exposed to normoxic (21% O

Indexed as

AnimalsAnimals, NewbornBronchopulmonary DysplasiaDisease Models, AnimalHyperoxiaLungRabbits

Identifiers

PMID34659632
PMCPMC8514964
OpenAlexW3204192180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.