Evidence map›Paper›PMID 34659624›Full record

ArticleThe World Allergy Organization journal2021

Prevalence and risk factors associated with allergic rhinitis in Mexican school children: Global Asthma Network Phase I.

Roberto García-Almaraz, Nayely Reyes-Noriega, Blanca Estela Del-Río-Navarro, Arturo Berber, Elsy Maureen Navarrete-Rodríguez, Philippa Ellwood, Luis García Marcos Álvarez, GAN Phase I group

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05330637 (Study on the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya, Hainan Province, China.), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05330637 unknown statusnot on this mapstarted 2022, after this paper: background citation

Study on the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya, Hainan Province, China.

TypeobservationalSponsorShanghai Jiao Tong University School of MedicineRan2022 to 2025Enrolled800ConditionsAsthma, Allergic Rhinitis, Chronic Obstructive Pulmonary Disease(COPD), Atopic DermatitisArmsClimate and environment in Sanya
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Prevalence and Sociodemographic Variation of Allergic Diseases in Australia: Findings From the Australian National Health Survey.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  2. Article
  3. Sexual Dimorphism in Allergic and Mast Cell-Associated Diseases.Clinical reviews in allergy & immunology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Roberto García-AlmarazHospital Infantil de Tamaulipas, Ciudad Victoria, Tamaulipas, Mexico.
Nayely Reyes-NoriegaServicio de Alergia e Inmunología, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Blanca Estela Del-Río-NavarroServicio de Alergia e Inmunología, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Arturo BerberAsesor Externo del Servicio de Alergia e Inmunología, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Elsy Maureen Navarrete-RodríguezServicio de Alergia e Inmunología, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
Philippa EllwoodDepartment of Paediatrics: Child and Youth Health, University of Auckland, Auckland 1023, New Zealand.
Luis García Marcos ÁlvarezPediatric Allergy and Pulmonology Units, 'Virgen de la Arrixaca' University Children's Hospital, University of Murcia, ARADyAL network and Biomedical Research Institute of Murcia (IMIB-Arrixaca), Murcia, Spain.
GAN Phase I group
Hospital Infantil de México Federico Gómez · MXAutonomous University of Tamaulipas · MXInstituto Murciano de Investigación Biosanitaria · ESUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe International Study of Asthma and Allergies in Childhood (ISAAC) showed a wide variability in prevalence and severity of allergic rhinitis (AR) and rhinoconjunctivitis (ARC), in addition to other atopic diseases (Asher et al, 2006).

objectiveTo estimate the prevalence of AR and ARC in children and adolescents in Mexico and to assess their association with different risk factors.

methodsGAN Phase I is a cross-sectional, multicentre survey carried out in 15 centres corresponding to 14 Mexican cities throughout 2016-2019 using the validated Spanish language version of the GAN Phase I questionnaires. The questionnaires were completed by 35 780 parents of 6-7 year old primary school pupils (children) and by 41 399 adolescents, 13-14 years old.

resultsThe current and cumulative prevalence of AR was higher in the adolescents (26.2-37.5%, respectively) in comparison to the children (17.9-24.9%, respectively), especially in female participants. This tendency was also observed in the current prevalence of ARC, where 15.1% of female adolescents reported nasal symptoms accompanied with itchy-watery eyes in the past year. The most important risk factors for AR and ARC were the presence of wheezing in the past 12 months, wheezing in the first year of life, the previous diagnosis of asthma and eczema symptoms. Furthermore, allergic symptoms had a negative tendency concerning altitude.

conclusionThis is the largest AR epidemiological study ever conducted in Mexico. It shows an increase in AR prevalence, as well as significant associations with modifiable risk factors, which could help to establish recommendations to reduce the burden of this condition.

Indexed as

Allergic rhinitisAR, Allergic rhinitisARC, Allergic rhino conjunctivitisGANGAN, Global asthma networkISAAC, International study of asthma and allergies in childhoodPrevalenceRhinoconjunctivitisRisk factors

Identifiers

PMID34659624
PMCPMC8495464
OpenAlexW3110660096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.