ReviewFrontiers in plant science2021
Phenoloxidases in Plants-How Structural Diversity Enables Functional Specificity.
Review in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Conserved 4-coumarate 3-hydroxylase/ascorbate peroxidase bifunctionality coordinates lignin deposition and plant growth in Brachypodium and Populus.Plant physiology · 2026Article
- Bio-stimulants for plant growth promotion and sustainable management of Rhizoctonia Solani causing black scurf of potato tubers.BMC plant biology · 2025Article
- Physiological roles of lignins - tuning cell wall hygroscopy and biomechanics.The New phytologist · 2025Review
- Biochemical Analysis of Recombinant Pea Seed Coat-Specific Polyphenol Oxidase (Journal of agricultural and food chemistry · 2025Article
- Bioinformatics and Functional Validation ofPlants (Basel, Switzerland) · 2025Article
- Gold nanoparticles synthesized from soil-derivedRSC advances · 2025Article
- Melatonin-inducedFrontiers in plant science · 2025Article
- Localization of Secondary Metabolites in Relict Gymnosperms of the GenusLife (Basel, Switzerland) · 2024Article
- Specific Substrate Activity of Lotus Root Polyphenol Oxidase: Insights from Gaussian-Accelerated Molecular Dynamics and Markov State Models.International journal of molecular sciences · 2024Article
- Article
- Applications of Nanozymes in Chiral-Molecule Recognition through Electrochemical and Ultraviolet-Visible Analysis.Molecules (Basel, Switzerland) · 2024Review
- Improved reference quality genome sequence of the plastic-degrading greater wax moth, Galleria mellonella.G3 (Bethesda, Md.) · 2024Article
- The PPO family in Nicotiana tabacum is an important regulator to participate in pollination.BMC plant biology · 2024Article
- Rosmarinic Acid and Flavonoids of the SeagrassPlants (Basel, Switzerland) · 2023Article
- Synthesis,Journal of enzyme inhibition and medicinal chemistry · 2023Article
- Phenoloxidases: catechol oxidase - the temporary employer and laccase - the rising star of vascular plants.Horticulture research · 2023Article
- Genome-Wide Association Study of Phenolic Content and Antioxidant Properties in Eggplant Germplasm.Genes · 2023Article
- Pathogenesis-Related Proteins (PRs) with Enzyme Activity Activating Plant Defense Responses.Plants (Basel, Switzerland) · 2023Review
- Components of the Phenylpropanoid Pathway in the Implementation of the Protective Effect of Sodium Nitroprusside on Wheat under Salinity.Plants (Basel, Switzerland) · 2023Article
- Different combinations of laccase paralogs nonredundantly control the amount and composition of lignin in specific cell types and cell wall layers in Arabidopsis.The Plant cell · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolism of polyphenolic polymers is essential to the development and response to environmental changes of organisms from all kingdoms of life, but shows particular diversity in plants. In contrast to other biopolymers, whose polymerisation is catalysed by homologous gene families, polyphenolic metabolism depends on phenoloxidases, a group of heterogeneous oxidases that share little beyond the eponymous common substrate. In this review, we provide an overview of the differences and similarities between phenoloxidases in their protein structure, reaction mechanism, substrate specificity, and functional roles. Using the example of laccases (LACs), we also performed a meta-analysis of enzyme kinetics, a comprehensive phylogenetic analysis and machine-learning based protein structure modelling to link functions, evolution, and structures in this group of phenoloxidases. With these approaches, we generated a framework to explain the reported functional differences between paralogs, while also hinting at the likely diversity of yet undescribed LAC functions. Altogether, this review provides a basis to better understand the functional overlaps and specificities between and within the three major families of phenoloxidases, their evolutionary trajectories, and their importance for plant primary and secondary metabolism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.