Evidence map›Paper›PMID 34659291›Full record

ArticleFrontiers in plant science2021

Comparative Transcriptome Analysis of Wheat Lines in the Field Reveals Multiple Essential Biochemical Pathways Suppressed by Obligate Pathogens.

Manuel Poretti, Alexandros G Sotiropoulos, Johannes Graf, Esther Jung, Salim Bourras, Simon G Krattinger, Thomas Wicker

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Manuel PorettiDepartment of Plant and Microbial Biology, University of Zürich, Zurich, Switzerland.
Alexandros G SotiropoulosDepartment of Plant and Microbial Biology, University of Zürich, Zurich, Switzerland.
Johannes GrafDepartment of Plant and Microbial Biology, University of Zürich, Zurich, Switzerland.
Esther JungDepartment of Plant and Microbial Biology, University of Zürich, Zurich, Switzerland.
Salim BourrasDepartment of Forest Mycology and Plant Pathology, Division of Plant Pathology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Simon G KrattingerKing Abdullah University of Science and Technology (KAUST), Biological and Environmental Science and Engineering Division (BESE), Thuwal, Saudi Arabia.
Thomas WickerDepartment of Plant and Microbial Biology, University of Zürich, Zurich, Switzerland.
University of Zurich · CHKing Abdullah University of Science and Technology · SASwedish University of Agricultural Sciences · SEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mildew and rust are the most devastating cereal pathogens, and in wheat they can cause up to 50% yield loss every year. Wheat lines containing resistance genes are used to effectively control fungal diseases, but the molecular mechanisms underlying the interaction between wheat and its fungal pathogens are poorly understood. Here, we used RNA sequencing (RNA-Seq) to compare the transcriptomic landscape of susceptible and resistant wheat lines to identify genes and pathways that are targeted by obligate biotrophic fungal pathogens. The five lines differed in the expression of thousands of genes under infection as well as control conditions. Generally, mixed infection with powdery mildew and leaf rust resulted in downregulation of numerous genes in susceptible lines. Interestingly, transcriptomic comparison between the nearly isogenic lines Thatcher and Thatcher-

Indexed as

compatible interactionfield trialobligate pathogensRNA-Seqwheat

Identifiers

PMID34659291
PMCPMC8513673
OpenAlexW3202546061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.