Evidence map›Paper›PMID 34659219›Full record

ArticleFrontiers in immunology2021

Poor CD4

Marija Zaric, Arianna Marini, Carolyn M Nielsen, Gaurav Gupta, David Mekhaiel, Thao P Pham, Sean C Elias, Iona J Taylor, Hans de Graaf, Ruth O Payne and 7 more

Open access · goldAbstract readClinical Trial, Phase I
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Efforts to Develop Pfs25 Vaccines.The American journal of tropical medicine and hygiene · 2022
    Article
  9. Article
  10. [Malarial antigens in the era of mRNA vaccines].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Marija ZaricNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Arianna MariniNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Carolyn M NielsenNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Gaurav GuptaNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
David MekhaielNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Thao P PhamLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rockville, MD, United States.
Sean C EliasNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Iona J TaylorNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Hans de GraafNIHR Clinical Research Facility, University Hospital Southampton NHS Foundation Trust and Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Ruth O PayneNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Yuanyuan LiNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Sarah E SilkNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Chris WilliamsNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Adrian V S HillNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
Carole A LongLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rockville, MD, United States.
Kazutoyo MiuraLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rockville, MD, United States.
Sumi BiswasNuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.
University of Oxford · GBJenner Institute · GBNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · USUniversity of Southampton · GB

Funding

Wellcome Trust 209200/Z/17/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunogenicity, VaccineAdolescentAdultAnimalsAntibodies, ProtozoanB-LymphocytesCD4-Positive T-LymphocytesCells, CulturedDisease Models, AnimalEpitopesFemaleHumansImmunity, HumoralMalaria, FalciparumMalaria VaccinesMaleAntibodies, ProtozoanEpitopesMalaria VaccinesProtozoan ProteinsRecombinant Proteinstransmission-Blocking Vaccine based on Pfs25CD4+P. falciparumPfs25transmission blockingvaccine

Identifiers

PMID34659219
PMCPMC8515144
OpenAlexW3204829583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.