Evidence map›Paper›PMID 34659211›Full record

ArticleFrontiers in immunology2021

Enhanced Susceptibility of ADAP-Deficient Mice to

Martha A L Böning, Gerald P Parzmair, Andreas Jeron, Henning P Düsedau, Olivia Kershaw, Baolin Xu, Borna Relja, Dirk Schlüter, Ildiko Rita Dunay, Annegret Reinhold and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. FYB1-targeted modulation of CAPG promotes AML progression.Molecular and cellular biochemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Martha A L BöningInfection Immunology, Institute of Medical Microbiology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Gerald P ParzmairInfection Immunology, Institute of Medical Microbiology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Andreas JeronInfection Immunology, Institute of Medical Microbiology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Henning P DüsedauInstitute of Inflammation and Neurodegeneration, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Olivia KershawDepartment of Veterinary Medicine, Institute of Veterinary Pathology, Freie Universität, Berlin, Germany.
Baolin XuExperimental Radiology, Department of Radiology and Nuclear Medicine, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Borna ReljaExperimental Radiology, Department of Radiology and Nuclear Medicine, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Dirk SchlüterInstitute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Ildiko Rita DunayInstitute of Inflammation and Neurodegeneration, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Annegret ReinholdInstitute of Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Burkhart SchravenInstitute of Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Dunja BruderInfection Immunology, Institute of Medical Microbiology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University, Magdeburg, Germany.
Otto-von-Guericke University Magdeburg · DEHelmholtz Centre for Infection Research · DECenter for Behavioral Brain Sciences · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adhesion and degranulation-promoting adaptor protein (ADAP) serves as a multifunctional scaffold and is involved in the formation of immune signaling complexes. To date, only limited data exist regarding the role of ADAP in pathogen-specific immunity during

Indexed as

Adaptor Proteins, Signal TransducingAnimalsDisease Models, AnimalDisease SusceptibilityFemaleImmunityListeria monocytogenesListeriosisLiverMaleMiceMice, KnockoutPhagocytesPhenotypeSpleenAdaptor Proteins, Signal TransducingFyb protein, mouseADAPadaptor proteininflammatory monocytesListeria monocytogenesneutrophil extracellular trapsneutrophilsphagocytosis

Identifiers

PMID34659211
PMCPMC8515145
OpenAlexW3203385435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.