Evidence map›Paper›PMID 34658867›Full record

ArticleFrontiers in pharmacology2021

Bruceae Fructus Oil Inhibits Triple-Negative Breast Cancer by Restraining Autophagy: Dependence on the Gut Microbiota-Mediated Amino Acid Regulation.

Jiyan Su, Xiaohong Chen, Yuanjie Xiao, Dan Li, Muxia Li, Hongfu Li, Jiangjian Huang, Zhengquan Lai, Ziren Su, Yizhen Xie and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Mechanisms Underlying the Therapeutic Effects ofInternational journal of genomics · 2025
    Article
  4. Review
  5. Review
  6. A review ofFrontiers in pharmacology · 2023
    Review
  7. Review
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  9. Major Constituents FromFrontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Jiyan SuAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Xiaohong ChenDepartment of Basic Medical Science, Xiamen Medical College, Xiamen, China.
Yuanjie XiaoDepartment of Cell Biology and Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, China.
Dan LiSchool of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, China.
Muxia LiSchool of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, China.
Hongfu LiThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Jiangjian HuangGuangzhou Baiyunshan Ming Xing Pharmaceutical Co., Ltd., Guangzhou, China.
Zhengquan LaiDepartment of Pharmacy, Shenzhen University General Hospital, Shenzhen University, Shenzhen, China.
Ziren SuSchool of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, China.
Yizhen XieGuangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, Guangdong Academy of Science, Guangzhou, China.
Dajiang ZhuAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Qianjun ChenDepartment of Breast Disease, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Hai LuDepartment of Breast Disease, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
Jingjin HeThe Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Chenglai XiaAffiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Guangzhou University of Chinese Medicine · CNEighth Affiliated Hospital of Sun Yat-sen UniversityInstitute of Microbiology · CNSouthern Medical University · CNFoshan Maternity and Child Health Care Hospital · CNJinan University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) has been acknowledged as an aggressive disease with worst prognosis, which requires endeavor to develop novel therapeutic agents. Bruceae fructus oil (BO), a vegetable oil derived from the fruit of

Indexed as

amino acid metabolismautophagyBruceae fructus oilgut microbiotamTORtriple-negative breast cancer

Identifiers

PMID34658867
PMCPMC8517338
OpenAlexW3204209694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.