Evidence map›Paper›PMID 34658863›Full record

ArticleFrontiers in pharmacology2021

Cimifugin Suppresses NF-κB Signaling to Prevent Osteoclastogenesis and Periprosthetic Osteolysis.

Juan Duan, Xuantao Hu, Tao Li, Gen Wu, Pengcheng Dou, Zhengxiao Ouyang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. [Cimifugin ameliorates Crohn's disease-like colitis in mice by modulating Th-cell immune balanceNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Juan DuanDepartment of Geriatric Internal Medicine, The Second Xiangya Hospital, Central South University, Changsha, China.
Xuantao HuDeparment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Tao LiDeparment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Gen WuDeparment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Pengcheng DouDeparment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhengxiao OuyangDeparment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aseptic prosthetic looseningcimifuginMAPKNF-κBosteoclastp38periprosthetic osteolysis

Identifiers

PMID34658863
PMCPMC8511420
OpenAlexW3162939804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.