Evidence map›Paper›PMID 34658836›Full record

ArticleFrontiers in aging neuroscience2021

The Effect of Mild Traumatic Brain Injury on Cerebral Microbleeds in Aging.

Luca Toth, Andras Czigler, Peter Horvath, Nikolett Szarka, Balint Kornyei, Arnold Toth, Attila Schwarcz, Zoltan Ungvari, Andras Buki, Peter Toth

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Traumatic brain injuries: a neuropsychological review.Frontiers in behavioral neuroscience · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Luca TothDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
Andras CziglerDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
Peter HorvathDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
Nikolett SzarkaInstitute for Translational Medicine, University of Pecs, Medical School, Pecs, Hungary.
Balint KornyeiDepartment of Radiology, University of Pecs, Medical School, Pecs, Hungary.
Arnold TothDepartment of Radiology, University of Pecs, Medical School, Pecs, Hungary.
Attila SchwarczDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
Zoltan UngvariDepartment of Biochemistry, Reynolds Oklahoma Center on Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
Andras BukiDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
Peter TothDepartment of Neurosurgery, University of Pecs, Medical School, Pecs, Hungary.
University of Pecs · HUSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A traumatic brain injury (TBI) induces the formation of cerebral microbleeds (CMBs), which are associated with cognitive impairments, psychiatric disorders, and gait dysfunctions in patients. Elderly people frequently suffer TBIs, especially mild brain trauma (mTBI). Interestingly, aging is also an independent risk factor for the development of CMBs. However, how TBI and aging may interact to promote the development of CMBs is not well established. In order to test the hypothesis that an mTBI exacerbates the development of CMBs in the elderly, we compared the number and cerebral distribution of CMBs and assessed them by analysing susceptibility weighted (SW) MRI in young (25 ± 10 years old,

Indexed as

agingcognitive declinemicrohemorragesmicrovascular injurytraumatic brain injury (TBI)

Identifiers

PMID34658836
PMCPMC8514735
OpenAlexW3204767304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.