ArticleInternational journal of mental health and addiction2021
Risk of First-Episode Schizophrenia in Aged Adults Increased During COVID-19 Outbreak.
Article in International journal of mental health and addiction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Psychosis during the COVID-19 pandemic: A systematic review of case reports and case series.Journal of psychiatric research · 2022Pooled it
- Unravelling the Viral Hypothesis of Schizophrenia: A Comprehensive Review of Mechanisms and Evidence.International journal of molecular sciences · 2025Review
- Influence of Healthcare Delivery Type on Patients' Mental Health: Is Hospitalization Always a Stressful Factor? Can Allostatic Load Help Assess a Patient's Psychological Disorders?Clinics and practice · 2024Article
- The Pandemic Paranoia Scale (PPS): factor structure and measurement invariance across languages.Psychological medicine · 2023Article
- Did Depression, Schizophrenia, and Alcohol Use Increase During the COVID-19 Pandemic Even in Low-Risk Regions? An Analysis of the 2017-2020 National Health Insurance Data in Tottori Prefecture.Yonago acta medica · 2023Article
- New-Onset Hyperreligiosity, Demonic Hallucinations, and Apocalyptic Delusions following COVID-19 Infection.Case reports in psychiatry · 2023Article
- Susceptibility and severity of COVID-19 and risk of psychiatric disorders in European populations: a Mendelian randomization study.Frontiers in psychiatry · 2023Article
- Risk Factors for Relapse in People with Severe Mental Disorders during the COVID-19 Pandemic: A Multicenter Retrospective Study.Healthcare (Basel, Switzerland) · 2021Article
- Analysis of the Consequences of the COVID-19 Pandemic on People with Severe Mental Disorders.International journal of environmental research and public health · 2021Article
- Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.Cell and tissue banking · 2020Review
- The potential impact of COVID-19 on psychosis: A rapid review of contemporary epidemic and pandemic research.Schizophrenia research · 2020Review
- COVID-19-Induced Psychosis and Suicidal Behavior: Case Report.SN comprehensive clinical medicine · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We noticed an unusual increase of aged adults in first-episode schizophrenia in January and February 2020 since the outbreak of COVID-19. This retrospective study aims to statistically validate this observation and find potential risk factors, if applicable. The demographics of schizophrenia in outpatients (both first-episode and follow-up) from January to March 2020 (36,624 records) and similar periods of 2017-2019 (114,141 records) were analyzed and compared to minimize seasonal influence. Limited personal information (age, gender, approximate residence) was investigated to find risk factors. After considering seasonal factors such as the Spring festival, the age of the first-episode schizophrenia was significantly increased in January (46.60 ± 15.14) and February (51.53 ± 14.74) but went back to normal in March 2020 (38.89 ± 14.59), compared with similar periods from 2017 to 2019 (Jan., 40.77 ± 15.26; Feb., 39.69 ± 15.10; Mar., 42.04 ± 15.83). Meanwhile, a slight but not significant change was found in the distribution of gender and approximate residence (urban/suburb). Our data supported that risk of first-episode schizophrenia in aged adults increased during the COVID-19 outbreak, which is consistent with the fact that COVID-19 is more lethal to elders. Public healthcare should prepare in advance for potential risks in public mental health, especially for elders.
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