Evidence map›Paper›PMID 34658452›Full record

ArticleTetrahedron letters2021

Using (+)-Carvone to access novel derivatives of (+)-

Alexandra E Golliher, Antonio J Tenorio, Nina O Dimauro, Nicolas R Mairata, F Omar Holguin, William Maio

Open access · greenAbstract read
In one paragraph

Article in Tetrahedron letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Carvone derived cannabidiol enantiomers as novel anticonvulsants.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alexandra E GolliherDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003.
Antonio J TenorioDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003.
Nina O DimauroDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003.
Nicolas R MairataDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003.
F Omar HolguinDepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003.
William MaioDepartment of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003.
New Mexico State University · US

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
NIGMS NIH HHS P20 GM103451
6 · The paper itself

Abstract

(-)-Cannabidiol [(-)-CBD] has recently gained prominence as a treatment for neuro-inflammation and other neurodegenerative disorders; interest is also developing in its synthetic enantiomer, (+)-CBD, which has a higher affinity to CB1 / CB2 receptors than the natural stereoisomer. We have developed an inexpensive, stereoselective route to access

Indexed as

Alkene TranspositionCannabidiol (CBD)Cannabidiphorol (CBDP)Cannabidivarin (CBDV)Enantiomer Natural Products

Identifiers

PMID34658452
PMCPMC8513745
OpenAlexW3127456147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.