Evidence map›Paper›PMID 34658417›Full record

ArticleJournal of fluid mechanics2021

The effect of Dean, Reynolds and Womersley numbers on the flow in a spherical cavity on a curved round pipe. Part 2. The haemodynamics of intracranial aneurysms treated with flow-diverting stents.

Michael C Barbour, Fanette Chassagne, Venkat K Chivukula, Nathanael Machicoane, Louis J Kim, Michael R Levitt, Alberto Aliseda

Abstract read
In one paragraph

Article in Journal of fluid mechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael C BarbourDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98107, USA.ORCID 0000-0001-5160-0119
Fanette ChassagneDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98107, USA.ORCID 0000-0002-4234-2784
Venkat K ChivukulaBiomedical and Chemical Engineering and Sciences, Florida Institute of Technology, Melbourne, FL 32901, USA.ORCID 0000-0002-8457-8509
Nathanael MachicoaneUniversity Grenoble Alpes, CNRS, Grenoble-INP, LEGI, F-38000, Grenoble, France.ORCID 0000-0001-6492-8412
Louis J KimDepartment of Neurological Surgery, University of Washington, Seattle, WA 98107, USA.ORCID 0000-0002-2544-5140
Michael R LevittDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98107, USA.ORCID 0000-0003-3612-3347
Alberto AlisedaDepartment of Mechanical Engineering, University of Washington, Seattle, WA 98107, USA.ORCID 0000-0002-5832-2999

Funding

Improving the computational modeling of coiled cerebral aneurysms through synchrotron microtomographyR01NS105692 · NINDS · UNIVERSITY OF WASHINGTON · PI Michael Robert Levitt · 2018 to 2026
$3.5M
Predicting cerebral aneurysm recurrence using Doppler guidewire measurementsR01NS088072 · NINDS · UNIVERSITY OF WASHINGTON · PI KIM, LOUIS JOONG · 2014 to 2018
$1.7M
Doppler flow wires and hemodynamics in intracranial aneurysmsR03NS078539 · NINDS · UNIVERSITY OF WASHINGTON · PI KIM, LOUIS JOONG · 2012 to 2013
$152k
American Heart Association-American Stroke Association 18CDA34110295NINDS NIH HHS R01 NS088072NINDS NIH HHS R01 NS105692NINDS NIH HHS R03 NS078539
6 · The paper itself

Abstract

The flow in a spherical cavity on a curved round pipe is a canonical flow that describes well the flow inside a sidewall aneurysm on an intracranial artery. Intracranial aneurysms are often treated with a flow-diverting stent (FDS), a low-porosity metal mesh that covers the entrance to the cavity, to reduce blood flow into the aneurysm sac and exclude it from mechanical stresses imposed by the blood flow. Successful treatment is highly dependent on the degree of reduction of flow inside the cavity, and the resulting altered fluid mechanics inside the aneurysm following treatment. Using stereoscopic particle image velocimetry, we characterize the fluid mechanics in a canonical configuration representative of an intracranial aneurysm treated with a FDS: a spherical cavity on the side of a curved round pipe covered with a metal mesh formed by an actual medical FDS. This porous mesh coverage is the focus of Part 2 of the paper, characterizing the effects of parent vessel

Indexed as

biomedical flowsblood flow

Identifiers

PMID34658417
PMCPMC8519511

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.