Evidence map›Paper›PMID 34658406›Full record

ArticleThe journal of extra-corporeal technology2021

Cell Saver Blood Reinfusion Up to 24 Hours Post Collection in Pediatric Cardiac Surgical Patients Does Not Increase Incidence of Hospital-Acquired Infections or Mortality.

Laura Boulos, Joseph D Kuebler, Ron Angona, Dawn Sweeney, Hongyue Wang, Elizabeth Nocera, Jill M Cholette

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of extra-corporeal technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Turbulence in surgical suction heads as detected by MRI.The journal of extra-corporeal technology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura BoulosDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Joseph D KueblerDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Ron AngonaDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Dawn SweeneyDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Hongyue WangDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Elizabeth NoceraDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Jill M CholetteDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Surgery, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; Department of Anesthesiology, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York; and Department of Biostatistics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York.
Golisano Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell saver blood reinfusion, a blood conservation technique recently available for pediatric use, is typically limited to 6 hours post processing to guard against bacterial contamination. We hypothesize that reinfusion of cell saver blood up to 24 hours post collection in children after cardiac surgery will not increase the incidence of hospital-acquired infections (HAI). The primary aim is to compare incidence of HAI between children receiving cell saver blood ≤6 hours vs. >6 to ≤24 hours from its collection. The secondary aim is to compare mortality and clinical outcomes. Retrospective chart review of children ≤18 years undergoing cardiac surgery with cardiopulmonary bypass (CPB) from 2013 to 2018 when cell saver collection and bedside temperature controlled storage became standard of care. Patients on extracorporeal membrane oxygenation (ECMO) within 48 hours postoperatively and those who did not receive cell saver were excluded. The primary outcome was HAI incidence postoperative days 0-6. Demographic data included diagnosis, surgical severity score, and clinical outcomes. 466 patients, 45% female. No significant between-group differences identified. There was no significant difference in HAI (control 8.5% vs. treatment 8.0%,

Indexed as

Blood Transfusion, AutologousCardiac Surgical ProceduresChildFemaleHospitalsHumansIncidenceMaleRetrospective Studiesblood conservationcell saverhospital-acquired infectiontransfusion

Identifiers

PMID34658406
PMCPMC8499635
OpenAlexW3205771360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.