Evidence map›Paper›PMID 34658340›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022

Impact of left ventricular outflow tract calcification in patients undergoing transfemoral transcatheter aortic valve implantation.

Lara Waldschmidt, Alina Goßling, Sebastian Ludwig, Matthias Linder, Lisa Voigtländer, David Grundmann, Oliver Bhadra, Till Demal, Johannes Schirmer, Hermann Reichenspurner and 5 more

Open access · greenAbstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Lara WaldschmidtDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Alina GoßlingDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Sebastian LudwigDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Matthias LinderDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Lisa VoigtländerDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
David GrundmannDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Oliver BhadraDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Till DemalDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Johannes SchirmerDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Hermann ReichenspurnerDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Stefan BlankenbergDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Dirk WestermannDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Moritz SeiffertDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Lenard ConradiDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Niklas SchoferDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Universität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular outflow tract (LVOT) calcification is known to be associated with adverse outcomes after transcatheter aortic valve implantation (TAVI) in patients receiving first-generation transcatheter heart valves (THV).

aimsThe aim of the present study was to assess the prevalence of LVOT calcification as well as its impact on outcomes in a contemporary TAVI patient cohort.

methodsThis retrospective single-centre analysis includes 1,207 patients who underwent transfemoral TAVI between 2012 and 2018 and in whom adequate contrast-enhanced multislice computed tomgraphy (MSCT) imaging for quantification of LVOT calcification was available.

resultsSignificant LVOT calcification, defined as >10 mm

conclusionsIn patients undergoing TAVI, the presence of significant LVOT calcification is common and associated with worse short-term clinical and functional outcomes as well as higher one-year mortality rates compared to patients w/o LVOT calcification.

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisTranscatheter Aortic Valve ReplacementAortic ValveCalcinosisHumansMultidetector Computed TomographyRetrospective StudiesTreatment Outcome

Identifiers

PMID34658340
PMCPMC9896403
OpenAlexW3205960781

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.