Evidence map›Paper›PMID 34658302›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes.

Helen K Reddel, Leonard B Bacharier, Eric D Bateman, Christopher E Brightling, Guy G Brusselle, Roland Buhl, Alvaro A Cruz, Liesbeth Duijts, Jeffrey M Drazen, J Mark FitzGerald and 11 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05609760 (Effects of an Automated System of Pictograms to Facilitate Comprehension of Medical Indications), which is not on this map. Cited by 246 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
246citing papers in PubMed, 8 pooled it
37.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05609760 naterminatednot on this map

Effects of an Automated System of Pictograms to Facilitate Comprehension of Medical Indications: A Randomised Trial

TypeinterventionalSponsorUniversidad de ConcepcionRan2022 to 2023Enrolled22ConditionsAsthma Chronic, Adherence, Medication, Primary Health CareArmsSIMAP, Usual Care
3 · Its place in the literature

Who cites it

246 citing papers in PubMed, 8 syntheses or guidelines pooled it, 446 citations in OpenAlex.

  1. Pooled it
  2. Quality of life of primary caregivers by severity and control of children's asthma: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  17. Circulating microRNAs Predict Longitudinal Asthma Control and Treatment Response.medRxiv : the preprint server for health sciences · 2026
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186 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 20 institutions in 13 countries.

Helen K ReddelThe Woolcock Institute of Medical Research and The University of Sydney, Sydney, Australia.ORCID 0000-0002-6695-6350
Leonard B BacharierMonroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0003-0432-2704
Eric D BatemanDepartment of Medicine, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-5064-5849
Christopher E BrightlingLeicester National Institute for Health Research Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.ORCID 0000-0002-9345-4903
Guy G BrusselleDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0001-7021-8505
Roland BuhlPulmonary Department, Mainz University Hospital, Mainz, Germany.
Alvaro A CruzFederal University of Bahia, Salvador, Bahia, Brazil.
Liesbeth DuijtsDepartment of Pediatrics, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands.ORCID 0000-0001-6731-9452
Jeffrey M DrazenDivisions of Medical Communication and Pulmonary Medicine, Department of Medicine, Brigham and Woman's Hospital, Boston, Massachusetts.ORCID 0000-0003-2715-9890
J Mark FitzGeraldUniversity of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-5367-5226
Louise J FlemingImperial College London, London, United Kingdom.ORCID 0000-0002-7268-7433
Hiromasa InoueKagoshima University, Kagoshima, Japan.ORCID 0000-0001-8080-3812
Fanny W KoThe Chinese University of Hong Kong, Hong Kong.ORCID 0000-0001-8454-0087
Jerry A KrishnanBreathe Chicago Center, University of Illinois Chicago, Chicago, Illinois.ORCID 0000-0001-5525-4778
Mark L LevyLocum General Practitioner, London, United Kingdom.ORCID 0000-0002-1807-3246
Jiangtao LinChina-Japan Friendship Hospital, Peking University, Beijing, China.ORCID 0000-0002-0228-572X
Kevin MortimerDepartment of Respiratory Medicine, Liverpool University Hospitals National Health Service Foundation Trust, United Kingdom.ORCID 0000-0002-8118-8871
Paulo M PitrezPediatric Respiratory Division, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0001-7319-1133
Aziz SheikhUsher Institute, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0001-7022-3056
Arzu A YorganciogluDepartment of Pulmonology, Celal Bayar University, Manisa, Turkey; and.ORCID 0000-0002-4032-0944
Louis-Philippe BouletInstitut universitaire de cardiologie et de pneumologie de Québec and.ORCID 0000-0003-3485-9393
Chinese University of Hong Kong · HKErasmus MC · NLGhent University Hospital · BEHarvard University · USHospital Moinhos de Vento · BRImperial College London · GBInstitut universitaire de cardiologie et de pneumologie de Québec · CAJohannes Gutenberg University Mainz · DEKagoshima University · JPManisa Celal Bayar University · TRMonroe Carell Jr. Children's Hospital · USNational Health Service · GBPeking University · CNThe University of Sydney · AUUniversidade Federal da Bahia · BRUniversity of British Columbia · CAUniversity of Cape Town · ZAUniversity of Edinburgh · GBUniversity of Illinois Chicago · USUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g., medication availability). This article summarizes key recommendations from GINA 2021, and the evidence underpinning recent changes. GINA recommends that asthma in adults and adolescents should not be treated solely with short-acting

Indexed as

AdolescentAdultAnti-Asthmatic AgentsAsthmaChildChild, PreschoolCombined Modality TherapyDisease ProgressionDrug Therapy, CombinationHumansInfantPatient AcuityPractice Guidelines as TopicRisk FactorsSelf CareAnti-Asthmatic Agentsasthmaasthma diagnosisasthma managementasthma prevention

Identifiers

PMID34658302
PMCPMC8865583
OpenAlexW3205425043

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.