Evidence map›Paper›PMID 34658147›Full record

ArticleJournal of biophotonics2022

Whole-organ transdermal photobiomodulation (PBM) of COVID-19: A 50-patient case study.

Richard K Williams, John Raimondo, David Cahn, Aldon Williams, Daniel Schell

Erratum issuedAbstract read
In one paragraph

Article in Journal of biophotonics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Photobiomodulation therapy.JADA foundational science · 2025
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Richard K WilliamsApplied BioPhotonics Ltd., Cupertino, California, USA.ORCID 0000-0001-5310-3167
John RaimondoPulmonair, San Antonio, Texas, USA.
David CahnO'Connor Hospital, San Jose, California, USA.
Aldon WilliamsAdvanced Spinal Pain Management, Boerne, Texas, USA.
Daniel SchellLightMD, Inc., Cupertino, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A nonrandomized 50-person case study of COVID-19-positive patients was conducted employing (for the first time) a regimen of whole-organ deep-tissue transdermal dynamic photobiomodulation (PBM) as a primary (or exclusive) therapeutic modality in the treatment of coronavirus. Therapy sessions comprised algorithmically alternating red (650 nm) and near-infrared (NIR; 850 nm) LEDs with an average irradiance of 11 mW/cm

Indexed as

COVID-19Low-Level Light TherapyHumansLungSARS-CoV-2ARDSCOVID-19dyspneamitochondriaphotobiomodulationred/NIR LEDSpO2transdermal

Identifiers

PMID34658147
PMCPMC8646787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.