Evidence map›Paper›PMID 34657908›Full record

ReviewInternal medicine (Tokyo, Japan)2021

Central Nervous System-related Graft-versus-host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Yuta Kaito, Shunsuke Yui, Kazuki Inai, Daishi Onai, Ryosuke Kinoshita, Satoshi Yamanaka, Muneo Okamoto, Ryuichi Wada, Ryuji Ohashi, Koiti Inokuchi and 1 more

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yuta KaitoDepartment of Hematology, Nippon Medical School, Japan.
Shunsuke YuiDepartment of Hematology, Nippon Medical School, Japan.
Kazuki InaiDepartment of Hematology, Nippon Medical School, Japan.
Daishi OnaiDepartment of Hematology, Nippon Medical School, Japan.
Ryosuke KinoshitaDepartment of Hematology, Nippon Medical School, Japan.
Satoshi YamanakaDepartment of Hematology, Nippon Medical School, Japan.
Muneo OkamotoDepartment of Hematology, Nippon Medical School, Japan.
Ryuichi WadaDepartment of Diagnostic Pathology, Nippon Medical School Hospital, Japan.
Ryuji OhashiDepartment of Integrated Diagnostic Pathology, Nippon Medical School, Japan.
Koiti InokuchiDepartment of Hematology, Nippon Medical School, Japan.
Hiroki YamaguchiDepartment of Hematology, Nippon Medical School, Japan.
Nippon Medical School · JPNippon Medical School Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic hemopoietic stem cell transplantation (allo-HSCT) is the only curative therapy for refractory hematological malignancies. However, there are many treatment-related complications, including organ disorders, graft-versus-host disease (GVHD), and infectious diseases. Furthermore, there are many unclear points regarding central nervous system (CNS) complications, and the prognosis in patients with CNS complications is extremely poor. We herein report a 49-year-old woman who developed CNS-GVHD after a second transplantation for therapy-related myelodysplastic syndrome. CNS-GVHD in this case was refractory to all treatments, including steroids, and progressed. We also present a review of the literature about the symptoms, diagnosis, and treatment of CNS-GVHD.

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationMyelodysplastic SyndromesCentral Nervous SystemFemaleHumansMiddle Agedallogeneic hematopoietic stem cell transplantationcentral nervous system complicationscentral nervous system graft-versus-host diseasegraft-versus-host disease

Identifiers

PMID34657908
PMCPMC8580761
OpenAlexW3206259425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.