Evidence map›Paper›PMID 34657613›Full record

ArticleBMC palliative care2021

Medical decisions concerning the end of life for cancer patients in three Colombian hospitals - a survey study.

Esther de Vries, Fabián Alexander Leal Arenas, Agnes van der Heide, Fritz E Gempeler Rueda, Raul Murillo, Olga Morales, Eduardo Diaz-Amado, Nelcy Rodríguez, Beatriz Juliana Gonzalez, Danny Steven Castilblanco Delgado and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC palliative care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Esther de VriesDepartment of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Cra. 7 No 40-62 Edificio Hospital San Ignacio, Piso 2, Bogota, Colombia. estherdevries@javeriana.edu.co.
Fabián Alexander Leal ArenasInstituto Nacional de Cancerología, Cl. 1 No 9-85, Bogota, Colombia.
Agnes van der HeideDepartment of Public Health, Erasmus MC University Medical Center Rotterdam, PO Box 2040, 3000, CA, Rotterdam, The Netherlands.
Fritz E Gempeler RuedaAnesthesiology Department, Pontificia Universidad Javeriana, Cra. 7 No 40-62 Edificio Hospital San Ignacio, Bogota, Colombia.
Raul MurilloCentro Javeriano de Oncología, Hospital Universitario San Ignacio, Carrera 7ª No. 40-62 Edificio Santacoloma (No 30), Bogota, Colombia.
Olga MoralesCentro Javeriano de Oncología, Hospital Universitario San Ignacio, Carrera 7ª No. 40-62 Edificio Santacoloma (No 30), Bogota, Colombia.
Eduardo Diaz-AmadoInstituto de Bioética, Pontificia Universidad Javeriana, Tv. 4 #42, Bogota, Colombia.
Nelcy RodríguezDepartment of Clinical Epidemiology and Biostatistics, Pontificia Universidad Javeriana, Cra. 7 No 40-62 Edificio Hospital San Ignacio, Piso 2, Bogota, Colombia.
Beatriz Juliana GonzalezCentro Javeriano de Oncología, Hospital Universitario San Ignacio, Carrera 7ª No. 40-62 Edificio Santacoloma (No 30), Bogota, Colombia.
Danny Steven Castilblanco DelgadoInstituto Nacional de Cancerología, Cl. 1 No 9-85, Bogota, Colombia.
Jose A CalvacheDepartment of Anesthesiology, Universidad del Cauca, Cl 5 #4-70, Popayán, Cauca, Colombia.
Hospital Universitario San Ignacio · COPontificia Universidad Javeriana · COErasmus MC · NLMilitary University Nueva Granada · COUniversity of Cauca · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer patients' end-of-life care may involve complex decision-making processes. Colombia has legislation regarding provision of and access to palliative care and is the only Latin American country with regulation regarding euthanasia. We describe medical end-of-life decision-making practices among cancer patients in three Colombian hospitals.

methodsCancer patients who were at the end-of-life and attended in participating hospitals were identified. When these patients deceased, their attending physician was invited to participate. Attending physicians of 261 cancer patients (out of 348 identified) accepted the invitation and answered a questionnaire regarding end-of-life decisions: a.) decisions regarding the withdrawal or withholding of potentially life-prolonging medical treatments, b.) intensifying measures to alleviate pain or other symptoms with hastening of death as a potential side effect, and c.) the administration, supply or prescription of drugs with an explicit intention to hasten death. For each question addressing the first two decision types, we asked if the decision was fully or partially made with the intention or consideration that it may hasten the patient's death.

resultsDecisions to withdraw potentially life-prolonging treatment were made for 112 (43%) patients, 16 of them (14%) with an intention to hasten death. For 198 patients (76%) there had been some decision to not initiate potentially life-prolonging treatment. Twenty-three percent of patients received palliative sedation, 97% of all patients received opioids. Six patients (2%) explicitly requested to actively hasten their death, for two of them their wish was fulfilled. In another six patients, medications were used with the explicit intention to hasten death without their explicit request. In 44% (n = 114) of all cases, physicians did not know if their patient had any advance care directives, 26% (n = 38) of physicians had spoken to the patient regarding the possibility of certain treatment decisions to hasten death where this applied.

conclusionsDecisions concerning the end of life were common for patients with cancer in three Colombian hospitals, including euthanasia and palliative sedation. Physicians and patients often fail to communicate about advance care directives and potentially life-shortening effects of treatment decisions. Specific end-of-life procedures, patients' wishes, and availability of palliative care should be further investigated.

Indexed as

Decision MakingNeoplasmsColombiaDeathHospitalsHumansSurveys and QuestionnairesCancerColombiaDecision makingEnd of lifeEuthanasiaMedical decisionPalliative carePalliative sedation

Identifiers

PMID34657613
PMCPMC8520825
OpenAlexW3197554461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.