Evidence map›Paper›PMID 34657368›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2022

Pregnancy and risk of COVID-19: a Norwegian registry-linkage study.

M C Magnus, L Oakley, H K Gjessing, O Stephansson, H M Engjom, F Macsali, P B Juliusson, A-M Nybo Andersen, S E Håberg

Open access · hybridAbstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. COVID-19 and Pregnancy: Key Findings.Scandinavian journal of immunology · 2026
    Review
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  19. Severe COVID-19 during pregnancy in Sweden, Norway, and Denmark.Acta obstetricia et gynecologica Scandinavica · 2023
    Article
  20. Pregnancy and COVID-19: past, present and future.Obstetrics & gynecology science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

M C MagnusCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-0568-3774
L OakleyCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
H K GjessingCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
O StephanssonDivision of Clinical Epidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
H M EngjomDepartment of Health Registry Research and Development, Norwegian Institute of Public Health, Oslo, Norway.
F MacsaliDepartment of Health Registry Research and Development, Norwegian Institute of Public Health, Oslo, Norway.
P B JuliussonDepartment of Health Registry Research and Development, Norwegian Institute of Public Health, Oslo, Norway.
A-M Nybo AndersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
S E HåbergCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Norwegian Institute of Public Health · NOKarolinska University Hospital · SEUniversity of Copenhagen · DK

Funding

Medical Research Council MC_UU_00011/6Norges Forskningsråd 262700Wellcome Trust 105545
6 · The paper itself

Abstract

objectiveTo compare the risk of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and contact with specialist healthcare services for coronavirus disease 2019 (COVID-19) between pregnant and non-pregnant women. POPULATION OR SAMPLE: All women ages 15-45 living in Norway on 1 March 2020 (n = 1 033 699).

methodsWe linked information from the national birth, patient, communicable diseases and education databases using unique national identifiers.

main outcome measureWe estimated hazard ratios (HR) among pregnant compared to non-pregnant women of having a positive test for SARS-CoV-2, a diagnosis of COVID-19 in specialist healthcare, or hospitalisation with COVID-19 using Cox regression. Multivariable analyses adjusted for age, marital status, education, income, country of birth and underlying medical conditions.

resultsPregnant women were not more likely to be tested for or to a have a positive SARS-CoV-2 test (adjusted HR 0.99; 95% CI 0.92-1.07). Pregnant women had higher risk of hospitalisation with COVID-19 (HR 4.70, 95% CI 3.51-6.30) and any type of specialist care for COVID-19 (HR 3.46, 95% CI 2.89-4.14). Pregnant women born outside Scandinavia were less likely to be tested, and at higher risk of a positive test (HR 2.37, 95% CI 2.51-8.87). Compared with pregnant Scandinavian-born women, pregnant women with minority background had a higher risk of hospitalisation with COVID-19 (HR 4.72, 95% CI 2.51-8.87).

conclusionPregnant women were not more likely to be infected with SARS-CoV-2. Still, pregnant women with COVID-19, especially those born outside of Scandinavia, were more likely to be hospitalised. TWEETABLE ABSTRACT: Pregnant women are at increased risk of hospitalisation for COVID-19.

Indexed as

Prenatal CareSARS-CoV-2AdolescentAdultCOVID-19FemaleHumansMiddle AgedNorwayPregnancyPregnancy Complications, InfectiousPregnancy OutcomeRegistriesRisk FactorsYoung AdultCOVID-19pregnancySARS-CoV-2

Identifiers

PMID34657368
PMCPMC8652518
OpenAlexW3206443730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.