Evidence map›Paper›PMID 34657242›Full record

Observational studyInternational urology and nephrology2022

Propensity-matched comparison of mortality between peritoneal dialysis and hemodialysis in patients with type 2 diabetes.

Hui Liu, Zhiren He, Xiaoxuan Hu, Shaoxue Li, Lixin Wang, Daixin Zhao, Qizhan Lin, Xusheng Liu, Fuhua Lu, Difei Zhang

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hui Liu *Department of Nephrology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Zhiren He *Department of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Xiaoxuan HuDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Shaoxue LiDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Lixin WangDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Daixin ZhaoDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Qizhan LinDepartment of Nephrology, Guangdong Provincial Hospital of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Xusheng LiuDepartment of Nephrology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China.
Fuhua LuDepartment of Nephrology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China. fuhualu_doctor@163.com.
Difei ZhangDepartment of Nephrology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, No.111 Dade Road, Guangzhou, 510120, China. zdf_doctor@163.com.
Guangzhou University of Chinese Medicine · CN

Funding

Project of Administration of Traditional Chinese Medicine of Guangdong Province of China No.20192028the Inheritance and Innovation of Traditional Chinese Medicine platform construction for Nephropathy No.01030315
6 · The paper itself

Abstract

backgroundThe optimal choice of dialysis modality for diabetic patients remains controversial. This study aimed to compare mortality between peritoneal dialysis (PD) and hemodialysis (HD) in end-stage renal disease (ESRD) patients with type 2 diabetes (T2D).

methodsOur observational, longitudinal cohort consisted of all incident ESRD patients with T2D who received either PD or HD in our center from January 2012 to December 2017 and were followed until December 2019. Propensity scores were used to select a 1:1 matched cohort. Mortality was compared between dialysis modalities using Kaplan-Meier survival analysis, and risk factors for mortality were estimated using multivariate Cox regression analyses.

resultsThe median follow-up times were 35.5 months in the PD group (n = 134) and 41.6 months in the HD group (n = 134, p = 0.0381). The 1-, 2-, 3-, 5-, and 7-year patient survival rates were 98%, 91%, 77%, 61%, and 35% for diabetic PD patients and 96%, 88%, 81%, 60%, and 57% for diabetic HD patients. Kaplan-Meier survival analysis showed that overall mortality did not significantly differ between modalities (log-rank = 0.9473, p = 0.6575). Using a multivariate Cox regression model, advanced age and increased cholesterol at the initiation of PD treatment were independent risk factors associated with mortality, whereas under HD therapy, the risk factors associated with mortality were lower BMI and higher HbA1c.

conclusionsThese results suggest that in patients with T2D, mortality is comparable between PD and HD irrespective of whether there are the first 2 years or over the 2-year period, and that different mortality predictor patterns exist between patients treated with PD versus HD.

Indexed as

Diabetes Mellitus, Type 2Kidney Failure, ChronicPeritoneal DialysisFemaleHumansKaplan-Meier EstimateMaleProportional Hazards ModelsRenal DialysisRetrospective StudiesRisk FactorsHemodialysisMortalityPeritoneal dialysisRisk factorsType 2 diabetes

Identifiers

PMID34657242
OpenAlexW3206362591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.