ArticleClinical oral investigations2022
Expanding the applications of photodynamic therapy-tooth bleaching.
Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- A Type I Aggregation-Induced Emission Photosensitizer Enables Peroxide-Free Photodynamic Tooth Whitening While Preserving Enamel Integrity.Journal of functional biomaterials · 2026Article
- Innovations in teeth bleaching: harnessing antimicrobial photodynamic therapy for enhanced outcomes.Lasers in medical science · 2025Review
- Review
- Feasibility and Safety of Adopting a New Approach in Delivering a 450 nm Blue Laser with a Flattop Beam Profile in Vital Tooth Whitening. A Clinical Case Series with an 8-Month Follow-Up.Journal of clinical medicine · 2024Article
- Dental Bleaching with Phthalocyanine Photosensitizers: Effects on Dentin Color and Collagen Content.Molecules (Basel, Switzerland) · 2023Article
- Pilot study on the applicability of boron-doped diamond electrodes for tooth whitening.Clinical and experimental dental research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe current tooth bleaching materials are associated with adverse effect. Photodynamic method based on a novel photosensitizer alone, without combining with peroxides, is evaluated for tooth bleaching application. MATERIALS AND
methodsTeeth samples were randomly divided into 3 groups with different treatment schemes, including negative control group (group A, physiological saline), experimental group (group B, ZnPc(Lys)
resultsThe color change values (ΔE) in group B (7.10 ± 1.03) and C (12.22 ± 2.35) were significantly higher than that in group A (0.93 ± 0.30, P < 0.05). Additionally, surface microhardness and roughness were significantly affected in group C, but not in the group A and B. Furthermore, the scanning electron microscope images showed no adverse effect of enamel in the group A and B while the group C demonstrated corrosive changes.
conclusionsZnPc(Lys) CLINICAL RELEVANCE: The current tooth bleaching materials give a satisfactory clinical outcome and long-term stability, but associated with some adverse reactions. Photosenstizer ZnPc(Lys)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.